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1,2-dichlorobenzene
go.drugbank.com/drugs/DB13963ApprovedWithdrawnThis derivative of benzene differs from the parent compound by the presence of two adjacent chlorine atoms. 1,2-dichlorobenzene is used as a precursor for agrochemicals, as a solvent for fullerenes, as … an insecticide and as an agent to remove carbon-based contamination from metal.
Benzylfentanyl
go.drugbank.com/drugs/DB09182ExperimentalIllicitIn 2010 it was removed from the list after it was found to have minimal opioid activity. … Benzylfentanyl has a Ki of 213nM at the mu opioid receptor, binding around 200x less strongly than fentanyl itself.
Setidegrasib
go.drugbank.com/drugs/DB21670InvestigationalThe usage of the INN stem '-rasib' in the name indicates that Setidegrasib is a Ras protein inhibitor. Setidegrasib has a monoisotopic molecular weight of 1116.48 Da.
POT-4
go.drugbank.com/drugs/DB06056InvestigationalThe investigational drug was under investigation in clinical trial NCT00473928 (Safety of Intravitreal POT-4 Therapy for Patients With Neovascular Age-Related Macular Degeneration (AMD) (ASaP)).
Sage oil
go.drugbank.com/drugs/DB11199ApprovedNutraceuticalEssential oil has been traditionally used in medicine for the relief of pain and the treatment of inflammation and infections, as it is reported to exhibit carminative, antispasmodic, antiseptic, and astringent
Dezocine
go.drugbank.com/drugs/DB01209ApprovedInvestigationalDezocine is a partial opiate drug and is used for pain management. Dezocine is a very effective alternative to fentanyl when administered during outpatient laparoscopy, although is associated with an increased incidence of postoperative ...
PX-478
go.drugbank.com/drugs/DB06082InvestigationalPX-478 was effective in models of both non-small cell lung cancer and small cell lung cancer that express HIF-1 alpha.
Tyrosinase
go.drugbank.com/drugs/DB16626InvestigationalA231829, A231834, A231839] Within mammals, tyrosinase is found specifically in melanocytes in a glycosylated form and plays a critical role in regulating the process of melanin biosynthesis (also known as … [A231829, A231839] It is recognized as being the main enzyme responsible for enzymatic browning and melanogenesis in mammals, thus causing undesired browning of fruits and vegetables and diseases resulting
Pagoclone
go.drugbank.com/drugs/DB04903InvestigationalPagoclone is an anxiolytic drug from the cyclopyrrolone family, which is related to other more well known drugs such as the sleeping medication zopiclone. … It is one of a relatively recently developed class of medicines known as the nonbenzodiazepines, which have similar effects to the older benzodiazepine group, but with quite different chemical structures