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ADP-A2M4CD8
go.drugbank.com/drugs/DB25733InvestigationalADP-A2M4CD8 is under investigation in clinical trial NCT04044859 (ADP-A2M4CD8 as Monotherapy or in Combination With Either Nivolumab or Pembrolizumab in HLA-A2+ Subjects With MAGE-A4 Positive Tumors (SURPASS
Difloxacin
go.drugbank.com/drugs/DB11511ExperimentalVet approvedAs an antibacterial, it presents a broad bactericidal spectrum and its effects are dependent on its concentration.
Tiletamine
go.drugbank.com/drugs/DB11549ExperimentalVet approvedTiletamine hydrochloride, the salt form, exists as odorless white crystals.
PZM21
go.drugbank.com/drugs/DB14030Experimentalnovel μ-opioid receptor (MOPr) ligand that has been reported to induce minimal arrestin recruitment and be devoid of the respiratory depressant effects characteristic of classical μ-opioid ligands such as
AM336
go.drugbank.com/drugs/DB06563ExperimentalIt was investigated as a potential treatment for various pain conditions.
ZYC300
go.drugbank.com/drugs/DB04986InvestigationalIt is designed as a vaccine, intended to increase immune system sensitivity to CYP1B1, an enzyme highly prevalent in tumor cells.
Tanespimycin
go.drugbank.com/drugs/DB05134InvestigationalTanespimycin, manufactured by Conforma Therapeutics is under development as a small molecule inhibitor of heat shock protein 90 (HSP90).
ABBV-514
go.drugbank.com/drugs/DB17586InvestigationalABBV-514 is in development for the treatment of non-small cell lung cancer (NSCLC) and head and neck squamous cell carcinoma (HNSCC) as a single agent and in combination with a PD-1 inhibitor.[L45464]
D-threo-neopterin
go.drugbank.com/drugs/DB02385Experimental(From Stedman, 26th ed) Neopterin also serves as a precursor in the biosynthesis of biopterin.
Brentuximab
go.drugbank.com/drugs/DB05471InvestigationalSGN-30 has demonstrated objective antitumor responses as a single agent in phase II clinical trials. … It is available commercially as the monoclonal antibody portion of the antibody-drug conjugate [brentuximab vedotin].