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Sipavibart
go.drugbank.com/drugs/DB21908ApprovedInvestigational[A274088] Sipavibart is approved for the pre-exposure prophylaxis treatment of COVID-19 in immunocompromised patients.[L53418] … [A274098] It works by binding to the SARS-CoV-2 spike protein receptor binding domain (RBD), neutralize the virus and preventing its entry into the host cell.
Categories: Antiinfectives for Systemic UseIcodextrin
go.drugbank.com/drugs/DB00702ApprovedInvestigationalIt is used primarily for ambulatory peritoneal dialysis (CAPD) of diabetic patients and automated peritoneal dialysis (APD) for patients with end-stage renal disease.
Categories: Compounds used in a research, industrial, or household settingDicloxacillin
go.drugbank.com/drugs/DB00485ApprovedInvestigationalVet approvedOne of the penicillins which is resistant to penicillinase.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseEnsitrelvir
go.drugbank.com/drugs/DB18834ApprovedInvestigationalEnsitrelvir is under investigation in clinical trial NCT05605093 (Strategies and Treatments for Respiratory Infections & Viral Emergencies (STRIVE): Shionogi Protease Inhibitor (Ensitrelvir)).
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseTroglitazone
go.drugbank.com/drugs/DB00197ApprovedWithdrawnIt was superseded by [pioglitazone] and [rosiglitazone].
Cethromycin
go.drugbank.com/drugs/DB06419Investigational[L14006, A203369] However, after completing phase III clinical trials, it was deemed safe but not sufficiently efficacious by the FDA. … [L13988] It has also been investigated, by itself or together with [zoliflodacin], for the treatment of gonorrhea,[A203432, A203495] and was recently suggested as a possible treatment for liver-stage _
2-ethylhexyl benzoate
go.drugbank.com/drugs/DB11291ApprovedWithdrawnMixtures: UV Capture Vita Sun Gel, UV Capture Sebum Control Sun CreamCentanafadine
go.drugbank.com/drugs/DB14841ApprovedInvestigational[L63806] Its mechanism in ADHD is unclear, but its efficacy may be mediated by this triple reuptake inhibition, which increases the availability of all three neurotransmitters in pathways involved in attention … age or weight.
Categories: Psychostimulants, Agents Used for ADHD and NootropicsEzatiostat
go.drugbank.com/drugs/DB05460InvestigationalThese are compounds containing an amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen … Many conditions are characterized by depleted bone marrow, including myelodysplastic syndrome (MDS), a form of pre-leukemia in which the bone marrow produces insufficient levels of one or more of the 3
Revakinagene taroretcel
go.drugbank.com/drugs/DB05344ApprovedInvestigational[A265115] On March 6, 2025, FDA approved revakinagene taroretcel for the treatment of idiopathic macular telangiectasia type 2. … encapsulated cell-based gene therapy that contains 200,000 to 440,000 allogeneic retinal pigment epithelial cells expressing recombinant human ciliary neurotropic factor (rhCNTF) (NTC-201-6A cell line) for