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Displaying results 3501 - 3510 of 4188 in total
  1. Drug

    9-(N-methyl-L-isoleucine)-cyclosporin A

    go.drugbank.com/drugs/DB13068
    Investigational

    9-(N-methyl-L-isoleucine)-cyclosporin A (NIM811) has been used in trials studying the treatment of Chronic Hepatitis C Genotype-1 Relapse.

  2. Drug

    Esomeprazole

    go.drugbank.com/drugs/DB00736
    ApprovedInvestigational

    Esomeprazole has been shown to inhibit acid secretion to a similar extent as [DB00338], without any significant differences between the two compounds _in vitro_. … [FDA Label] PPIs such as esomeprazole have also been shown to inhibit the activity of dimethylarginine dimethylaminohydrolase (DDAH), an enzyme necessary for cardiovascular health.

  3. Drug

    MK-8776

    go.drugbank.com/drugs/DB11899
    Investigational

    Sch 900776 has been used in trials studying the treatment of Neoplasms, Hodgkin Disease, Adult Erythroleukemia, Lymphoma, Non-Hodgkin, and Myelogenous Leukemia, Acute, among others.

  4. Drug

    Inclacumab

    go.drugbank.com/drugs/DB12246
    Investigational

    Inclacumab has been used in trials studying the treatment and prevention of Myocardial Infarction, Peripheral Arterial Disease (PAD), and Coronary Heart Disease, Graft Occlusion, Vascular.

  5. Drug

    Tetrahydrouridine

    go.drugbank.com/drugs/DB12484
    Investigational

    Tetrahydrouridine has been used in trials studying the treatment of Neoplasms, Lung Neoplasms, Breast Neoplasms, Sickle Cell Disease, and Head and Neck Cancer, among others.

  6. Drug

    Molgramostim

    go.drugbank.com/drugs/DB12525
    Investigational

    Molgramostim has been used in trials studying the treatment of Bronchiectasis, Cystic Fibrosis, Pulmonary Alveolar Proteinosis, Acute Respiratory Distress Syndrome, and Autoimmune Pulmonary Alveolar Proteinosis

  7. Drug

    AFN-1252

    go.drugbank.com/drugs/DB12658
    Investigational

    AFN-1252 has been used in trials studying the treatment of Cellulitis, Burn Infection, Wound Infection, Cutaneous Abscess, and Skin and Subcutaneous Tissue Bacterial Infections.

  8. Drug

    Foxy-5

    go.drugbank.com/drugs/DB13034
    Investigational

    Foxy-5 has been used in trials studying the treatment of Prostate Cancer, Colorectal Cancer, Metastatic Colon Cancer, Metastatic Breast Cancer, and Metastatic Prostate Cancer.

  9. Drug

    TSHA-118

    go.drugbank.com/drugs/DB16996
    Experimental

    TSHA-118 is a self-complementary AAV9 gene replacement therapy designed to express a human codon-optimized CLN1 transgene for the treatment of CLN1 disease.

  10. Target

    Diacylglycerol O-acyltransferase 1

    go.drugbank.com/bio_entities/BE0012021
    TargetHumans

    Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates (PubMed:16214399, PubMed:18768481, PubMed:28420705, PubMed:32433610, PubMed:32433611, PubMed:9756920). H...

    Synonyms: ACAT-related gene product 1