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Testolactone
go.drugbank.com/drugs/DB00894ApprovedWithdrawnAn antineoplastic agent that is a derivative of progesterone and used to treat advanced breast cancer.
Synonyms: D-homo-17a-oxaandrosta-1,4-diene-3,17-dioneAdipose-Derived Mesenchymal Stem Cells: Autologous or Allogeneic Origins
go.drugbank.com/drugs/DB15729InvestigationalAutologous stem cells are those derived from a patient’s own cells while allogeneic stem cells are derived from that of a donor. … Lipoaspiration, also known as liposuction, is a possible method for extraction. This is followed by purification and expansion of the cells in vitro.
Synonyms: Adipose-Derived Mesenchymal Stem Cells: Autologous or Allogeneic OriginsDalbavancin
go.drugbank.com/drugs/DB06219ApprovedInvestigationalDalbavancin acts by interfering with bacterial cell wall synthesis by binding to the D-alanyl-D-alanine terminus of nascent cell wall peptidoglycan and preventing cross-linking [FDA Label, F2356, A4072 … Dalbavancin is a second-generation lipoglycopeptide antibiotic that was designed to improve on the natural glycopeptides currently available, such as vancomycin and teicoplanin [A4072, A4073].
Reviparin
go.drugbank.com/drugs/DB09259ApprovedReviparin has a molecular weight of 3.9 kDa.[A32021] It was developed by Abbott laboratories and in 2009, reviparin presented an orphan drug designation by the FDA.[L1469] … Reviparin is a low molecular weight heparin which seems to have a better safety profile than unfractionated heparin.
Products: CLIVARIN 5726 IE A XA/ML, CLIVARODI 17178 A XA/MLFluoroazomycin arabinoside F-18
go.drugbank.com/drugs/DB15134InvestigationalFluoroazomycin arabinoside F-18 is under investigation in clinical trial NCT03257150 (A Study of the Use of Irreversible Electroporation in Pancreatic Ductal Cancer).
Categories: Compounds used in a research, industrial, or household setting, Diagnostic Uses of ChemicalsAmitraz
go.drugbank.com/drugs/DB11373ExperimentalVet approvedAmitraz presents a lower effect in mammals and thus, it is widely used in the treatment of mite- or tick-infestation of dogs. … Its insecticide effect is due to its agonistic activity in the alpha-adrenergic system, its interaction with the octopamine receptors in the central nervous system and its driven inhibition of the synthesis
Synonyms: 1,5-di(2,4-dimethylphenyl)-3-methyl-1,3,5-triazapenta-1,4-dieneCategories: Compounds used in a research, industrial, or household settingPentaerythritol tetranitrate
go.drugbank.com/drugs/DB06154ApprovedWithdrawnIt is a vasodilator with properties that are quite similar to those of glyceryl trinitrate, however, with a more prolonged duration of action. … It is also one of the most powerful high explosives known and is a component of the plastic explosive known as Semtex [L2393]. PETN has the chemical formula C5H8N4O12.
Synonyms: Tetranitrato de pentaeritritilo, Tetranitrate de pentaerithrityleAEOL-10150
go.drugbank.com/drugs/DB05874ExperimentalAEOL 10150 is developed by Aeolus as a therapeutic agents based on its proprietary small molecule catalytic antioxidants.
Categories: Heterocyclic Compounds with 4 or More RingsMequitazine
go.drugbank.com/drugs/DB01071InvestigationalIt provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory allergies. … Mequitazine is a histamine H1 antagonist (antihistamine).
CHGN111
go.drugbank.com/drugs/DB06376ExperimentalNumerous parameters of mitochondrial function are altered when the activity of CLK-1 is reduced, which results in a decrease of ROS at critical cellular sites, as well as in a decrease of systemic oxidative … CHGN111 is an inhibitor of the mitochondrial enzyme CLK-1 which is a demethoxyubiquinone hydroxylase.