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Tianeptine
go.drugbank.com/drugs/DB09289InvestigationalTianeptine is a drug used primarily in the treatment of major depressive disorder and has been studied in the treatment of irritable bowel syndrome (IBS) . Structurally, it is classified as a tricyclic antidepressant (TCA), however, it p...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesDigoxin Immune Fab (Ovine)
go.drugbank.com/drugs/DB00076ApprovedIt is used as an antidote for overdose of digoxin.
Rupatadine
go.drugbank.com/drugs/DB11614ApprovedInvestigationalRupatadine is a dual histamine H1 receptor and platelet activating factor receptor antagonist that is used for symptomatic relief in seasonal and perennial rhinitis as well as chronic spontaneous urticaria … It was approved for marketing in Canada under the tradename Rupall and comes in tablet formulation for adult use and liquid formulation for pediatric use.
Categories: Antihistamines for Systemic Use, Cytochrome P-450 SubstratesPF-05230907
go.drugbank.com/drugs/DB18417InvestigationalPF-05230907 is a recombinant activated Factor X variant.
PA-1050040
go.drugbank.com/drugs/DB06039ExperimentalPA1050040, a second generation HIV-1 maturation inhibitor, is a chemical analog of Bevirimat (BVM). It inhibits virus replication by the same mechanism of action as BVM.
Benzthiazide
go.drugbank.com/drugs/DB00562ApprovedThiazides also cause loss of potassium and an increase in serum uric acid.
Glafenine
go.drugbank.com/drugs/DB08963ApprovedWithdrawnAn anthranilic acid derivative with analgesic properties used for the relief of all types of pain. Glafenine is withdrawn from the American market.
Molnupiravir
go.drugbank.com/drugs/DB15661Investigational[A193029] Recent studies have shown molnupiravir inhibits replication of human and bat coronaviruses, including SARS-CoV-2, in mice and human airway epithelial cells. … [A193026] The active drug incorporates into the genome of RNA viruses, leading to an accumulation of mutations known as viral error catastrophe.
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseIndinavir
go.drugbank.com/drugs/DB00224ApprovedInvestigationalA potent and specific HIV protease inhibitor that appears to have good oral bioavailability. [PubChem]
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic Use