Search

Displaying results 3511 - 3520 of 8469 in total
  1. Drug

    Lenvatinib

    go.drugbank.com/drugs/DB09078
    ApprovedInvestigational

    In particular, VEGF has been identified as a crucial regulator of both physiologic and pathologic angiogenesis and increased expression of VEGF is associated with a poor prognosis in many types of cancers … These receptor tyrosine kinases (RTKs) located in the cell membrane play a central role in the activation of signal transduction pathways involved in the normal regulation of cellular processes, such as

  2. Drug

    Ferric pyrophosphate citrate

    go.drugbank.com/drugs/DB13995
    Approved

    Free iron presents several side effects as it can catalyze free radical formation and lipid peroxidation as well as the presence of interactions of iron in plasma. … [A31979] FPC is categorized in Japan as a second class OTC drug.

  3. Drug

    Elafin

    go.drugbank.com/drugs/DB05161
    Investigational

    The excellent tolerability of Elafin in human subjects was demonstrated in a Phase I clinical single dose escalating study.

  4. Drug

    Inosinic Acid

    go.drugbank.com/drugs/DB04566
    Investigational

    A purine nucleotide which has hypoxanthine as the base and one phosphate group esterified to the sugar moiety.

  5. Drug

    NOX-700

    go.drugbank.com/drugs/DB05464
    Experimental

    It has since been found that oxidative signaling of the redox-sensitive transcription factor, NF-κB, and inhibiting protein glycation are responsible for the drug's therapeutic effects.

  6. Drug

    Masoprocol

    go.drugbank.com/drugs/DB00179
    Investigational

    It also serves as an antioxidant in fats and oils. [PubChem]

  7. Drug

    Taliglucerase alfa

    go.drugbank.com/drugs/DB08876
    Approved

    It was approved in 2012 and is marketed under the name Elelyso for use in patients with type 1 Gaucher's disease.

  8. Drug

    Ferric subsulfate

    go.drugbank.com/drugs/DB13885
    Approved

    It has the chemical formula Fe4(OH)2(SO4)5. It is used after superficial skin biopsies.

  9. Drug

    Gedatolisib

    go.drugbank.com/drugs/DB11896
    ApprovedInvestigational

    Celcuity describes gedatolisib as the first FDA-approved therapy to inhibit the pathway comprehensively across all class I PI3K isoforms and both mTOR complexes. … [L63927] Its approval also addresses a population defined by the absence of a biomarker, as patients with PIK3CA wild-type disease were not eligible for the PI3Kα-selective options.

  10. Drug

    1,2-Benzodiazepine

    go.drugbank.com/drugs/DB12537
    ApprovedInvestigationalWithdrawn

    Benzodiazepine has been investigated for the treatment of Obesity, Sleep Apnea, Obstructive, and Disorders of Gallbladder, Biliary Tract and Pancrease.