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Alefacept
go.drugbank.com/drugs/DB00092ApprovedWithdrawnProduced by CHO cells, mW is 91.4 kD. … Immunosuppressive dimeric fusion protein that consists of the extracellular CD2-binding portion of the human leukocyte function antigen-3 (LFA-3) linked to the Fc (hinge, CH2 and CH3 domains) portion of
Categories: CD2-directed LFA-3/Fc Fusion ProteinCoagulation Factor IX (Recombinant)
go.drugbank.com/drugs/DB00100Approvedmedium that is then processed and purified for use as a pharmaceutical agent. … Recombinant Coagulation Factor IX is a purified Factor IX glycoprotein produced by recombinant DNA technology.
Products: OCTANINE® F 500 UI, OCTANINE F ® 250 UIBecaplermin
go.drugbank.com/drugs/DB00102ApprovedInvestigationalBecaplermin has a molecular weight of approximately 25 KD and is a homodimer composed of two identical polypeptide chains that are bound together by disulfide bonds. … Becaplermin is produced by recombinant DNA technology by insertion of the gene for the B chain of platelet derived growth factor (PDGF) into the yeast, Saccharomyces cerevisiae.
Categories: Proto-Oncogene Proteins c-sisSynonyms: SH-POLYPEPTIDE-59, PDGF-2Agalsidase beta
go.drugbank.com/drugs/DB00103ApprovedInvestigationalAgalsidase beta is a recombinant human α-galactosidase A similar to [agalsidase alfa]. … [A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa, after a contamination event in 2009.
Products: ฟาบราไซม์ (5 มก.), REPLAGAL 1 MG/ML IV İNFÜZYONLUK KONSANTRE ÇÖZELTİ, 1 ADETBevacizumab
go.drugbank.com/drugs/DB00112ApprovedInvestigationalThere is a great deal of evidence indicating that vascular endothelial growth factor (VEGF) is important for the survival and proliferation of cancer cells. … [A192834,A192888,A192837,A192891,A192894] Bevacizumab is a humanized monoclonal IgG antibody that inhibits angiogenesis by binding and neutralizing VEGF-A.
Synonyms: 贝伐珠单抗International brands: 安倍斯, 安维汀Technetium Tc-99m arcitumomab
go.drugbank.com/drugs/DB00113ExperimentalThe molecule has a molecular weight of ~54,000 Daltons. … Reduced Fab fragment of the murine IgG1 monoclonal antibody IMMU-4 (also called NP-4) with specificity for carcinoembryonic antigen (CEA) covalently labeled with Technitium 99.
Acarbose
go.drugbank.com/drugs/DB00284ApprovedInvestigationalAcarbose is a complex oligosaccharide that acts as an inhibitor of several enzymes responsible for the breakdown of complex carbohydrates in the intestines. … Acarbose is therefore used in conjunction with diet, exercise, and other pharmacotherapies for the management of blood sugar levels in patients with type 2 diabetes.
Products: GLUCOBAY® 50MG TABLETAS, GLUCOBAY® 100MG TABLETASCapreomycin
go.drugbank.com/drugs/DB00314ApprovedInvestigationalIt is produced by Streptomyces capreolus.
Categories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexPyrazinamide
go.drugbank.com/drugs/DB00339ApprovedInvestigationalA pyrazine that is used therapeutically as an antitubercular agent.
Mixtures: RINCURE ® 3 FDC TABLETAS CON PELICULA, PRO TB 4Categories: Heterocyclic Compounds, 1-RingSucralfate
go.drugbank.com/drugs/DB00364ApprovedInvestigationalSucralfate is a medication that is widely used to prevent and treat a number of diseases in the gastrointestinal tract such as duodenal ulcers [FDA label], gastro-esophageal reflux disease (GERD), gastritis … Sucralfate has been shown to be a well-tolerated and safe drug. It is sold under many brands and is available in both tablet and suspension forms.
Mixtures: CARDIBID®100/200 MG TABLETA RECUBIERTASynonyms: Hexadeca-μ-hydroxytetracosahydroxy[μ8-[1,3,4,6-tetra-O-sulfo-β-Dfructofuranosyl-α-D-glucopyranoside tetrakis(hydrogen sulfato)8-)]]hexadecaaluminum