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Displaying results 3511 - 3520 of 10000 in total
  1. Drug

    Zetomipzomib

    go.drugbank.com/drugs/DB16070
    Investigational

    Zetomipzomib is under investigation in clinical trial NCT04033926 (A Phase 2 Study of KZR-616 to Evaluate Safety and Efficacy in Patients With Active Polymyositis or Dermatomyositis).

    Synonyms: (2S,3R)-N-[(2S)-3-(cyclopent-1-en-1-yl)-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]-3-hydroxy-3-(4-methoxyphenyl)-2-[(2S)-2-[2-(morpholin-4-yl)acetamido]propanamido]propanamideCategories: Heterocyclic Compounds, 1-Ring
  2. Drug

    Encaleret

    go.drugbank.com/drugs/DB18096
    Investigational

    Synonyms: 2'-((1r)-1-(((1-(4-chloro-3-fluorophenyl)-2-methylpropan-2-yl)amino)-(2r)-2-hydroxypropoxy)ethyl)-3-methyl(1,1'-biphenyl)-4-carboxylic acid, 2'-((1r)-1-(((2r)-3-((1-(4-chloro-3-fluorophenyl)-2-methylpropan-2-yl)amino)-2-hydroxypropyl)oxy)ethyl)-3-methyl-1,1'-biphenyl-4-carboxylic acid
  3. Drug

    Bexotegrast

    go.drugbank.com/drugs/DB16515
    Investigational

    PLN-74809 is a small-molecule that dually inhibits both α<sub>v</sub>β<sub>6</sub> and α<sub>v</sub>β<sub>1</sub> to treat both idiopathic pulmonary fibrosis (IPF) and primary sclerosing cholangitis (PSC … The compound was granted orphan drug designation by the US FDA in August 2018 for treatment of IPF, and Pliant Therapeutics recently raised $100 million in Series C financing to support further clinical

    Synonyms: (2S)-4-(2-METHOXYETHYL-(4-(5,6,7,8-TETRAHYDRO-1,8-NAPHTHYRIDIN-2-YL)BUTYL)AMINO)-2-(QUINAZOLIN-4-YLAMINO)BUTANOIC ACID, (S)-4-[(2-Methoxyethyl)[4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butyl]amino]-2-[(quinazolin-4-yl)amino]butanoic acid
  4. Drug

    Cetermin

    go.drugbank.com/drugs/DB32081
    Experimental

    Synonyms: Tgf-.beta.2 (human), Transforming growth factor-beta 2
  5. Drug

    Anthranilic acid

    go.drugbank.com/drugs/DB04166
    Investigational

    Synonyms: 2-Aminobenzoesäure, 2-carboxyaniline
  6. Drug

    Picolinic acid

    go.drugbank.com/drugs/DB05483
    Experimental

    It acts as an anti-infective and immunomodulator and is produced in approximately 25-50 mg quantities by the body on a daily basis through the breakdown of tryptophan. … PCL-016 plays a key role in zinc transport.

    Synonyms: 2-CarboxypyridineCategories: Heterocyclic Compounds, 1-Ring, Compounds used in a research, industrial, or household setting
  7. Drug

    SYD-003

    go.drugbank.com/drugs/DB17106
    Experimental

    Synonyms: (5-amino-1-(4-fluoro-phenyl)-1h-pyrazol-4-yl)-(3-(2,3-dihydroxy-propoxy)-phenyl)-methanone, [5-Amino-1-(4-fluoro-phenyl)-1H-pyrazol-4-yl]-[3-(2,3-dihydroxy-propoxy)-phenyl]-methanoneCategories: Heterocyclic Compounds, 1-Ring
  8. Drug

    Coenzyme A

    go.drugbank.com/drugs/DB01992
    InvestigationalNutraceutical

    All genomes sequenced to date encode enzymes that use coenzyme A as a substrate, and around 4% of cellular enzymes use it, or a thioester form of it, as a substrate. … Coenzyme A (CoA, CoASH, or HSCoA) is a coenzyme, well known for it's role in the synthesis and oxidation of fatty acids, and the oxidation of pyruvate in the citric acid cycle.

    Synonyms: 3'-phosphoadenosine-(5')diphospho(4')pantatheine, Coenzyme ACategories: Heterocyclic Compounds, 2-Ring, Coenzyme A, biosynthesis
  9. Drug

    R107474

    go.drugbank.com/drugs/DB06553
    Experimental

    Synonyms: 3-(2-(3,4-Dihydrobenzofuro(3,2-c)pyridin-2(1H)-yl)ethyl)-2-methyl-4H-pyrido(1,2-a)pyrimidin-4-one, 3-[2-(3,4-dihydro-1H-[1]benzofuro[3,2-c]pyridin-2-yl)ethyl]-2-methylpyrido[1,2-a]pyrimidin-4-oneCategories: Heterocyclic Compounds, 1-Ring
  10. Drug

    Fipaxalparant

    go.drugbank.com/drugs/DB18124
    Investigational

    Synonyms: 1h-indene-2-carboxylic acid, 2,3-dihydro-2-((4-methoxy-3-(2-(3-methylphenyl)ethoxy)benzoyl)amino)-