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Displaying results 3511 - 3520 of 10000 in total
  1. Drug

    Josamycin

    go.drugbank.com/drugs/DB01321
    Investigational

    A macrolide antibiotic from Streptomyces narbonensis. The drug has antimicrobial activity against a wide spectrum of pathogens.

    Synonyms: leucomycin V 3-acetate 4B-(3-methylbutanoate), leucomycin V 3-acetate 4β-(3-methylbutanoate)Products: Josalid 250 mg/5 ml - Saft für Kinder, Josalid 375 mg/5 ml - Saft für Kinder
  2. Target

    Aclacinomycin 10-hydroxylase RdmB

    go.drugbank.com/bio_entities/BE0002526
    TargetStreptomyces purpurascens

    In vivo and in vitro, RdmB catalyzes the removal of the carboxylic group from the C-10 position of 15-demethoxyaclacinomycin T coupled to hydroxylation at the same C-10 position. … It could also catalyze the removal of the carboxylic group at the C-10 position of 15-demethoxy-epsilon-rhodomycin coupled to hydroxylation at the same C-10 position to yield rhodomycin B.

    Polypeptides: Aclacinomycin 10-hydroxylase RdmBSynonyms: 15-demethoxy-epsilon-rhodomycin 10-hydroxylase
  3. Target

    Immunoglobulin superfamily member 10

    go.drugbank.com/bio_entities/BE0004612
    TargetHumans

    Involved in the control of early migration of neurons expressing gonadotropin-releasing hormone (GNRH neurons) (By similarity). May be involved in the maintenance of osteochondroprogenitor cells pool (By similarity)

    Polypeptides: Immunoglobulin superfamily member 10
  4. Drug

    Carboprost tromethamine

    go.drugbank.com/drugs/DB00429
    ApprovedInvestigational

    A nonsteroidal abortifacient agent that is effective in both the first and second trimesters of pregnancy.

    Synonyms: 1,3-dihydroxy-2-(hydroxymethyl)propan-2-aminium (5Z,9α,11β,13E,15S)-9,11,15-trihydroxy-15-methylprosta-5,13-dien-1-oate, 15(S)-15-methyl-PGF2α tromethamine saltCategories: Prostaglandins F, Synthetic
  5. Drug

    Butenafine

    go.drugbank.com/drugs/DB01091
    Approved

    Butenafine hydrochloride is a synthetic benzylamine antifungal agent. Butenafine's mechanism of action is believed to involve the synthesis inhibition of sterols.

    Synonyms: N-(p-tert-butylbenzyl)-N-methyl-1-naphthalenemethylamine, (4-tert-Butyl-benzyl)-methyl-naphthalen-1-ylmethyl-amineProducts: BUTAFLY % 1 LOSYON ,10 ML, BUTEFIN %1 KREM, 30 G
  6. Drug

    Dosulepin

    go.drugbank.com/drugs/DB09167
    ApprovedInvestigational

    It is not FDA-approved due to low therpeutic index and significant toxicity in overdose. … Dosulepin inhibits the reuptake of biogenic amines, increasing available neurotransmitter levels at the synaptic cleft.

    Synonyms: (3E)-3-dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethylpropan-1-amine, 11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenzo(b,e)thiepinCategories: Serotonin 5-HT1 Receptor Antagonists, Serotonin 5-HT2 Receptor Antagonists
  7. Drug

    Brodalumab

    go.drugbank.com/drugs/DB11776
    ApprovedInvestigational

    Brodalumab has been used in trials studying the treatment of Asthma, Psoriasis, Crohn's Disease, Psoriatic Arthritis, and Rheumatoid Arthritis. Brodalumab was FDA approved in February, 2017 as Siliq for the treatment of moderate-to-sever...

    Categories: Interleukin-17 Receptor A Antagonist, Interleukin 17 Receptor A AntagonistsProducts: LUMICEF SUBCUTANEOUS INJECTION 210 MG SYRINGE
  8. Drug

    Trametinib

    go.drugbank.com/drugs/DB08911
    ApprovedInvestigational

    [A258298] It was later approved by Health Canada on July 18, 2013 [L45588] and by the European Commission on June 30, 2014. … Trametinib is an orally bioavailable mitogen-activated extracellular signal-regulated kinase 1 (MEK1) and MEK2 inhibitor.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingProducts: MEKINIST 2 MG FILM KAPLI TABLET ,TABLET, 30 ADET, MEKINIST 0.5 MG FILM KAPLI TABLET ,TABLET, 30 ADET
  9. Drug

    Gentian violet cation

    go.drugbank.com/drugs/DB00406
    Approved

    A dye that is a mixture of violet rosanilinis with antibacterial, antifungal, and anthelmintic properties.

    Mixtures: Kerr 100 Triple Dye Dispos-ASynonyms: Crystal violet(1+), Gentian violet(1+)
  10. Drug

    Erythropoietin

    go.drugbank.com/drugs/DB00016
    ApprovedInvestigational

    It has a molecular weight of approximately 30,400 daltons and is produced by mammalian cells into which the human erythropoietin gene has been introduced. … It works by promoting the division and differentiation of committed erythroid progenitors in the bone marrow [FDA Label].

    Synonyms: 1-165-Erythropoietin (human clone λHEPOFL13 protein moiety), glycoform αProducts: Binocrit 10 000 IU/1 ml solution for injection in a pre-filled syringe, EPORON 10000 IU/1,0 ML KULLANIMA HAZIR 10 ENJEKTOR