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Displaying results 3531 - 3540 of 10000 in total

Drug
Zoniporide
go.drugbank.com/drugs/DB20312
Experimental
Zoniporide is a small molecule drug. The usage of the INN stem '-poride' in the name indicates that Zoniporide is a Na+/H+ antiport inhibitor. … Zoniporide has a monoisotopic molecular weight of 320.14 Da.
Categories: Heterocyclic Compounds, 1-Ring
Drug
LI-301
go.drugbank.com/drugs/DB05509
Experimental
LI 301 is an orally bio-available compound delivered in a fast melt mechanism with taste masking enabling it to be taken anytime without water. … It has a novel mode of action combining both the light effect of a Selective Serotonin Reuptake Inhibitor ("SSRI")(most likely antagonistic at 5HT1a receptors) and antagonism at mu-opioid receptors.
Drug
Ceftiofur
go.drugbank.com/drugs/DB11485
ExperimentalVet approved
E. coli strains resistant to ceftiofur have been reported. … Ceftiofur is a third generation cephalosporin antibiotic, first described in 1987, and now used in veterinary medicine.
Categories: Heterocyclic Compounds, 2-Ring
Drug
Acetohexamide
go.drugbank.com/drugs/DB00414
ApprovedWithdrawn
A sulfonylurea hypoglycemic agent that is metabolized in the liver to 1-hydrohexamide. Acetohexamide has been discontinued in the US market.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesSynonyms: 1-((p-Acetylphenyl)sulfonyl)-3-cyclohexylurea, 1-[(4-acetylbenzene)sulfonyl]-3-cyclohexylurea 4-acetyl-N-(cyclohexylcarbamoyl)benzenesulfonamide
Drug
Isoflurane
go.drugbank.com/drugs/DB00753
ApprovedInvestigationalVet approved
A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
Synonyms: 1-chloro-2,2,2-trifluoroethyl difluoromethyl etherCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 Inducers
Drug
Ertapenem
go.drugbank.com/drugs/DB00303
ApprovedInvestigational
Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics.[L14339] It was first authorized for use in the US in November 2001 and in Europe in April 2002. … [A447] Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic bacteria, ertapenem is used to treat various bacterial infections.
Synonyms: (1R,5S,6S,8R,2'S,4'S)-2-(2-(3-carboxyphenylcarbamoyl)pyrrolidin-4-ylthio)-6-(1-hydroxyethyl)-1-methylcarbapenem-3-carboxylic acid, (4R,5S,6S)-3-((3S,5S)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acidCategories: Heterocyclic Compounds, 2-Ring
Drug
Fidexaban
go.drugbank.com/drugs/DB19562
Experimental
Fidexaban has a monoisotopic molecular weight of 526.18 Da. … Fidexaban is a small molecule drug. The usage of the INN stem '-xaban' in the name indicates that Fidexaban is a blood coagulation factor XA inhibitor, antithrombotic.
Categories: Heterocyclic Compounds, 1-Ring
Drug
Denileukin diftitox
go.drugbank.com/drugs/DB00004
ApprovedInvestigational
approved to treat a human disease in the US. … Denileukin diftitox is an IL2-receptor-directed cytotoxin, is a recombinant DNA-derived fusion protein composed of the amino acid sequences for diphtheria toxin fragments A and B (Met<sub>1</sub>-Thr<sub
Synonyms: N-L-METHIONYL-387-L-HISTIDINE-388-L-ALANINE-1-388-TOXIN (CORYNEBACTERIUM DIPHTHERIAE STRAIN C7) (388->2') PROTEIN WITH 2-133-INTERLEUKIN 2 (HUMAN CLONE PTIL2-21A), N-MET-187-HIS-388-ALA-1-388-TOXIN (CORYNEBACTERIUM DIPHTHERIAE C7) WITH 1-133-INTERLEUKIN 2
Drug
Methoxyflurane
go.drugbank.com/drugs/DB01028
ApprovedInvestigationalVet approvedWithdrawn
If so employed, it should be administered with nitrous oxide to achieve a relatively light level of anesthesia, and a neuromuscular blocking agent given concurrently to obtain the desired degree of muscular
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: PENTHROX®, Penthrop 99,9%, 3 ml Flüssigkeit zur Herstellung eines Dampfs zur Inhalation
Drug
Human papillomavirus type 31 L1 capsid protein antigen
go.drugbank.com/drugs/DB10310
ApprovedInvestigational
Human papillomavirus type 31 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. … It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 31.
Synonyms: L1 protein, Human papillomavirus type 31 Vaccine, Human papillomavirus type 31 L1 capsid protein antigenMixtures: GARDASIL® 9 VACUNA RECOMBINANTE NONAVALENTE CONTRA EL VIRUS DEL PAPILOMA HUMANO, GARDASIL® 9 VACUNA RECOMBINANTE NONAVALENTE CONTRA EL VIRUS DEL PAPILOMA HUMANO