Search
Clesrovimab
go.drugbank.com/drugs/DB18877ApprovedClesrovimab is a fully human immunoglobulin G1 kappa (IgG1κ) monoclonal antibody targeted against the extracellular domain of the respiratory syncytial virus (RSV) fusion (F) protein. … [A273953,A273978] Clesrovimab-cfor was approved by the US FDA in June 2025 for use in infants prior to or during their first RSV season.[L53228,L53233]
Categories: Respiratory Syncytial Virus Anti-F Protein Monoclonal AntibodySynonyms: Immunoglobulin g1 (262-tyrosine,264-threonine,266-glutamic acid), anti-(human respiratory syncytial virus f protein) (human monoclonal rb1 .gamma.1-chain), disulfide with human monoclonal rb1 .kappa.Dengue virus serotype 2
go.drugbank.com/drugs/DB22665Approved[L53368] Qdenga was approved for use in the European Union in December 2022.[L53373] … Dengue virus serotype 2 is a serotype of _Orthoflavivirus denguei_ known to cause dengue fever.
Synonyms: Dengue virus type 2, Dengue virus serotype 2Dengue virus serotype 3
go.drugbank.com/drugs/DB22666Approved[L53368] Qdenga was approved for use in the European Union in December 2022.[L53373] … Dengue virus serotype 3 is a serotype of _Orthoflavivirus denguei_ known to cause dengue fever.
Synonyms: Dengue virus type 3, Dengue virus serotype 3Pexidartinib
go.drugbank.com/drugs/DB12978ApprovedInvestigational[A182240,L7901] Debilitating symptoms often follow with tenosynovial giant cell tumors, along with a risk of significant functional limitations and a reduced quality of life in patients. … In clinical trials, pexidartinib was shown to promote improvements in patient symptoms and functional outcomes in TGCT.
Categories: MATE 1 Inhibitors, MATE 2 InhibitorsTranylcypromine
go.drugbank.com/drugs/DB00752ApprovedInvestigationalIt also is useful in panic and phobic disorders (From AMA Drug Evaluations Annual, 1994, p311). … Tranylcypromine is a racemate comprising equal amounts of (1R,2S)- and (1S,2R)-2-phenylcyclopropan-1-amine with the chiral centers both located on the cylopropane ring.
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Cytochrome P-450 CYP1A2 InhibitorsSynonyms: (1R*,2S*)-2-phenylcyclopropan-1-amine, (±)-trans-2-phenylcyclopropylamineDioxybenzone
go.drugbank.com/drugs/DB11221ApprovedWithdrawnDioxybenzone is an approved sunscreen ingredient in concentrations up to 3% [L2525]. … Dioxybenzone, or benzophenone-8, is an organic compound derived from [DB01878] that is used as a sunscreen agent. It absorbed UV-B and UV-AII rays.
Synonyms: 2,2'-Dihydroxy-4-methoxybenzophenoneFluoxymesterone
go.drugbank.com/drugs/DB01185ApprovedIllicitAn anabolic steroid that has been used in the treatment of male hypogonadism, delayed puberty in males, and in the treatment of breast neoplasms in women.
Synonyms: 9-Fluoro-11β,17β-dihydroxy-17-methylandrost-4-en-3-one, 11β,17β-Dihydroxy-9α-fluoro-17α-methyl-4-androster-3-oneInternational brands: U-GonoBufexamac
go.drugbank.com/drugs/DB13346ApprovedWithdrawnThe use of bufexamac has been discontinued in Canada and the United States, which may be due to undetermined clinical efficacy and a high prevalence of contact sensitization [A32822]. … It has also been used in suppositories in combination with local anaesthetics indicated for haemorrhoids.
Synonyms: 4-Butoxy-N-hydroxybenzeneacetamide, 2-(p-Butoxyphenyl)-acetohydroxamic acidCategories: Non COX-2 selective NSAIDSRetifanlimab
go.drugbank.com/drugs/DB15766ApprovedInvestigational[L45603,L45613] The use of retifanlimab in combination with other oncology drugs for the treatment of metastatic gastroesophageal adenocarcinoma has also been evaluated.[A258383,A258388] … Retifanlimab is a humanized IgG4 kappa monoclonal antibody that binds to the programmed death receptor-1 (PD-1), blocking PD-1 interaction with its ligands, programmed death-ligand 1 (PD-L1) and programmed
Categories: PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsSynonyms: Anti-PD-1 monoclonal antibody MGA012Motexafin gadolinium
go.drugbank.com/drugs/DB05428InvestigationalMotexafin gadolinium is studied in the treatment of cancer by Pharmacyclics. … It belongs to the family of drugs called metalloporphyrin complexes. Also called gadolinium texaphyrin.
Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-Ring