Fluoxymesterone is a synthetic androgenic anabolic steroid that used in the treatment of hypogonadism and delayed puberty in males, as well as breast neoplasms in women. A medication used to treat conditions related to low levels of male hormones and terminal breast cancer in women.
- Mechanism
- Curator reviewed
Fluoxymesterone is a synthetic androgenic anabolic steroid and is approximately 5 times as potent as natural methyltestosterone. Like testosterone and other androgenic hormones, fluoxymesterone binds to the androgen receptor. It produces retention of nitrogen, sodium, potassium, and phosphorus; increases protein anabolism; decreases amino acid catabolism and decreased urinary excretion of calcium. The antitumour activity of fluoxymesterone appears related to reduction or competitive inhibition of prolactin receptors or estrogen receptors or production.
- Primary indication
- In males, used as replacement therapy in conditions associated with symptoms of deficiency or absence of endogenous testosterone.Curator reviewed · 7 structured indications
- Formula / weight
- C20H29FO3 · 336.4409 g/mol (avg)
- First approval
- Canada, 2003 · United States, 1983
- Code names
- NSC-12165
- Brand names
Resolves to
YLRFCQOZQXIBAB-RBZZARIASA-NSMILES[H][C@@]12CC[C@](C)(O)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)CC[C@]12CWhat you can answer from here — as of September 23, 2026
Which drugs share a target with Fluoxymesterone, and which of those have an active Phase 3 trial?
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