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Oleoyl-estrone
go.drugbank.com/drugs/DB04870InvestigationalOleoyl-estrone (OE) is a fatty acid ester of estrone. This hormone occurs naturally and is found circulating in various animal species and humans. … Body protein loss is an unpleasant effect of fat loss by the restriction of calories, and studies show that this drug appears to avoid this effect.
Synonyms: OECOVID19 s-vax loaded autologous dendritic cell vaccine
go.drugbank.com/drugs/DB15814ExperimentalThe rationale is that loading a DC cell with SARS-Cov-2 antigens and administering it as a vaccine can induce a more prolific immune response. … As of May 2020, the company is pursuing a human clinical trial (ChiCTR2000033003) to test the safety and immunogenicity of the vaccine.
Piritramide
go.drugbank.com/drugs/DB12492ApprovedWithdrawnPiritramide is under investigation for the treatment of Colon Cancer and Minimal Residual Disease. … Piritramide has been investigated for the supportive care of Pain, Postoperative and Postoperative Nausea and Vomiting.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeAtaluren
go.drugbank.com/drugs/DB05016ApprovedWithdrawnMore specifically, ataluren is used in the small group of patients whose disease is caused by a specific genetic defect (called a ‘nonsense mutation’) in the dystrophin gene. … Ataluren is a novel, orally administered drug that targets nonsense mutations.
Pegaptanib
go.drugbank.com/drugs/DB04895ApprovedWithdrawnPegaptanib was granted FDA approval on 17 September 2004.[L17903] … Pegaptanib is a polynucleotide aptamer. Pegatinib aids neovascular age-related macular degeneration by binding to VEGF which in order reduces angiogenesis and vessel permeability.
Categories: Vascular Endothelial Growth Factor ADroloxifene
go.drugbank.com/drugs/DB15641ExperimentalDroloxifene has an anti-implantation effect in rats, and the effect appears to be not completely due to its anti-estrogenic activity.[L34184] … Droloxifene, a derivative of the triphenylethylene drug tamoxifen, is a novel selective estrogen receptor modulator (SERM).
Categories: Compounds used in a research, industrial, or household settingTaliglucerase alfa
go.drugbank.com/drugs/DB08876ApprovedTaliglucerase alfa is the recombinant active form of the human lysosomal enzyme, β-glucocerebrosidase.
Synonyms: prGC-DProducts: ELELYSO 200 U İNFÜZYONLUK SOLÜSYON İÇİN LİYOFİLİZE TOZ, 1 ADETVusolimogene oderparepvec
go.drugbank.com/drugs/DB23008ApprovedInvestigationalon a PD-1-blocking antibody-based regimen. … killing and GM-CSF promoting dendritic cell and monocyte activation to drive an anti-tumor immune response.
Trilostane
go.drugbank.com/drugs/DB01108ApprovedVet approvedWithdrawnTrilostane is an inhibitor of 3 beta-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome. It was withdrawn from the United States market in April 1994.