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Valbenazine
go.drugbank.com/drugs/DB11915ApprovedInvestigationalThe reduction in chorea severity was observed as early as 2 weeks after starting treatment with an initial dose of 40 mg.[L47910] … [A261125] On August 2023, valbenazine was again approved by the FDA for the treatment of chorea associated with Huntington's disease respectively.
Sucralose
go.drugbank.com/drugs/DB15049InvestigationalSucralose is an artificial sweetener used as a sugar substitute.
Categories: Compounds used in a research, industrial, or household settingPantethine
go.drugbank.com/drugs/DB11190ApprovedIt consists of two molecules of pantetheine that form a dimer via disufide linkages, and acts as an intermediate in the production of Coenzyme A. … Coenzyme A plays an essential role as a cofactor in the metabolism of lipids and carbohydrates including fatty acid oxidation, carbohydrate metabolism, pyruvate degradation, and amino acid catabolism [
Synonyms: D-Bis(N-pantothenyl-beta-aminoethyl) disulfidePalonosetron
go.drugbank.com/drugs/DB00377ApprovedInvestigationalPalonosetron (INN, trade name Aloxi) is an antagonist of 5-HT3 receptors that is indicated for the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). … It is the most effective of the 5-HT3 antagonists in controlling delayed CINV nausea and vomiting that appear more than 24 hours after the first dose of a course of chemotherapy and is the only drug of
Oleoyl-estrone
go.drugbank.com/drugs/DB04870InvestigationalThis hormone occurs naturally and is found circulating in various animal species and humans. … It has been shown in animal studies to promote the loss of body fat while maintaining body protein storage, maintaining nitrogen balance.
Temefos
go.drugbank.com/drugs/DB12231InvestigationalDiphos has been used in trials studying the treatment of Plasmodium Falciparum Malaria.
Categories: Compounds used in a research, industrial, or household settingLumefantrine co-artemether
go.drugbank.com/drugs/DB13085ApprovedInvestigationalWithdrawnThe combination is an effective and well-tolerated malaria treatment, providing high cure rates even in areas of multi-drug resistance. … Unlike artemether, lumefantrine has a slower onset of action, resulting in clearance of residual parasites and a decrease in recrudescence rate.
Defibrotide
go.drugbank.com/drugs/DB04932ApprovedInvestigationalIt is marketed under the brand names Dasovas (FM), Noravid, and Prociclide in a variety of countries. In the USA it is was approved in March, 2016 as Defitelio.
Cannabinor
go.drugbank.com/drugs/DB05048ExperimentalCannabinor, a synthetic CB2-selective agonist, is in Phase 2 clinical testing as an analgesic.
Pefloxacin
go.drugbank.com/drugs/DB00487ApprovedA synthetic broad-spectrum fluoroquinolone antibacterial agent active against most gram-negative and gram-positive bacteria.