Temefos

DB12231InvestigationalSmall molecule

Diphos has been used in trials studying the treatment of Plasmodium Falciparum Malaria.

Mechanism: Pharmacologically active on Acetylcholinesterase
Curator reviewed
Formula / weight: C₁₆H₂₀O₆P₂S₃ · 466.46 g/mol (avg)
Also known as: Diphos
Code names: AC-52160 · EI-52160 · ENT-27165

Resolves to

Compound

Structure

InChIKeyWWJZWCUNLNYYAU-UHFFFAOYSA-NSMILESCOP(=S)(OC)OC1=CC=C(SC2=CC=C(OP(=S)(OC)OC)C=C2)C=C1

Targets

What you can answer from here — as of August 09, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

388Drug interactionsStructured to mechanism, not free text

2Clinical trialsPhase, status and sponsor resolved per trial

1+ReferenceStructured and connected to the statements they support

Which drugs share a target with Temefos, and which of those have an active Phase 3 trial?

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