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Displaying results 3561 - 3570 of 10000 in total

Drug
Calusterone
go.drugbank.com/drugs/DB01564
ExperimentalIllicit
A 17-alkylated orally active androgenic steroid. A Schedule IV drug in Canada.
Synonyms: 17beta-Hydroxy-7beta,17-dimethylandrost-4-en-3-one
Drug
Lumiliximab
go.drugbank.com/drugs/DB06162
Investigational
Lumiliximab is a chimeric monoclonal antibody which is used as an immunosuppressive drug. … Clinical trials for CLL were terminated in 2010, and for allergic asthma in 2007. Results published from the CLL clinical trial failed to meet primary endpoints.
Synonyms: IMMUNOGLOBULIN G1, ANTI-(HUMAN IMMUNOGLOBULIN E RECEPTOR TYPE II) (HUMAN-MACACA IRUS MONOCLONAL IDEC-152 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MACACA IRUS MONOCLONAL IDEC-152 .KAPPA.-CHAIN, DIMER, IMMUNOGLOBULIN G1, ANTI-(HUMAN IMMUNOGLOBULIN E RECEPTOR TYPE II) (HUMAN-MACACA IRUS MONOCLONAL IDEC-152 .GAMMA.1-CHAIN), DISULPHIDE WITH HUMAN-MACACA IRUS MONOCLONAL IDEC-152 .KAPPA.-CHAIN, DIMER
Drug
Caprylic alcohol
go.drugbank.com/drugs/DB12452
Investigational
Caprylic alcohol has been used in trials studying the treatment of Essential Tremor.
Categories: Compounds used in a research, industrial, or household setting
Drug
Leptin
go.drugbank.com/drugs/DB05098
Investigational
Although leptin is a circulating signal that reduces appetite, in general, obese people have an unusually high circulating concentration of leptin. … Thus, obesity develops when people take in more energy than they use over a prolonged period of time, and this excess food intake is not driven by hunger signals, occurring in spite of the anti-appetite
Drug
Florquinitau (18F)
go.drugbank.com/drugs/DB19215
Approved
Florquinitau F 18 is a radioactive diagnostic drug used as a fluorine-18–labeled positron emission tomography (PET) tracer. … [L64052] It binds to aggregated tau protein, which in Alzheimer's disease forms the neurofibrillary tangles (NFTs) that are one of the two components required for a neuropathological diagnosis of the disease
Drug
Alatrofloxacin
go.drugbank.com/drugs/DB09335
ApprovedWithdrawn
Alatrofloxacin is a fluoroquinolone antibiotic developed by Pfizer, delivered as a mesylate salt. It was withdrawn from the U.S. market in 2001.
Categories: Topoisomerase II Inhibitors
Drug
Paromomycin
go.drugbank.com/drugs/DB01421
ApprovedInvestigational
An oligosaccharide antibiotic produced by various streptomyces. [PubChem]
Synonyms: Paromomycin I, Monomycin A
Drug
Axitinib
go.drugbank.com/drugs/DB06626
ApprovedInvestigational
[A179398] It is most commonly marketed under the name Inlyta® and is available in oral formulations. … Axitinib is a second generation tyrosine kinase inhibitor that works by selectively inhibiting vascular endothelial growth factor receptors (VEGFR-1, VEGFR-2, VEGFR-3).
Categories: UGT1A1 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexSynonyms: N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamide
Drug
CYT006-AngQb
go.drugbank.com/drugs/DB05739
Investigational
CYT006-AngQb is a therapeutic vaccine in development for treatment of hypertension. … It is designed to instruct the patient’s immune system to produce an antibody response against angiotensin II, a small peptide that causes blood vessels to narrow and results in increased blood pressure
Drug
Terbinafine
go.drugbank.com/drugs/DB00857
ApprovedInvestigationalVet approved
Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. … [A1279] Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell wall
Synonyms: (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalene methanamine, (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethylamineProducts: SOLVEASY TINEA SPRAY 1% w/w, SOLVEASY TINEA CREAM 1% w/w