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Displaying results 3581 - 3590 of 10000 in total
  1. Pathway

    Acylcarnitine 5-Methylhexanoylcarnitine

    smpdb.ca/view/SMP0123831
    Metabolic

    5-Methylhexanoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 5-methylhexanoyl-CoA reacts with L-carnitine to form 5-methylhexanoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5
  2. Pathway

    Acylcarnitine 5-Hydroxydodecanedioylcarnitine

    smpdb.ca/view/SMP0124080
    Metabolic

    5-Hydroxydodecanedioylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 5-hydroxydodecanedioyl-CoA reacts with L-carnitine to form 5-hydroxydodecanedioylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5
  3. Pathway

    Acylcarnitine 5-Hydroxypentadecanoylcarnitine

    smpdb.ca/view/SMP0124226
    Metabolic

    5-Hydroxypentadecanoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 5-hydroxypentadecanoyl-CoA reacts with L-carnitine to form 5-hydroxypentadecanoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5
  4. Pathway

    Acylcarnitine 5-hydroxyoctadecanoylcarnitine

    smpdb.ca/view/SMP0124314
    Metabolic

    5-hydroxyoctadecanoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 5-hydroxyoctadecanoyl-CoA reacts with L-carnitine to form 5-hydroxyoctadecanoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5
  5. Drug

    Epoprostenol

    go.drugbank.com/drugs/DB01240
    ApprovedInvestigational

    A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from prostaglandin endoperoxides in human vascular tissue.

    Synonyms: (5Z,13E)-(15S)-6,9alpha-Epoxy-11alpha,15-dihydroxyprosta-5,13-dienoate, (5Z,9α,11α,13E,15S)-6,9-epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acidCategories: Prostaglandins I
  6. Drug

    Sapropterin

    go.drugbank.com/drugs/DB00360
    ApprovedInvestigational

    tryptophan to 5-hydroxytryptophan via tryptophan hydroxylase. … Sapropterin (tetrahydrobiopterin or BH4) is a cofactor in the synthesis of nitric oxide.

    Categories: P-glycoprotein inhibitors, Heterocyclic Compounds, 2-RingSynonyms: 2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)-pteridinone, (−)-(6R)-2-amino-6-((1R,2S)-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4(3H)-pteridinone
  7. Drug

    Lisdexamfetamine

    go.drugbank.com/drugs/DB01255
    ApprovedInvestigational

    Lisdexamfetamine is a prodrug of [dextroamphetamine], a central nervous system stimulant known as d-amphetamine,[A40246] covalently attached to the naturally occurring amino acid L-lysine. … [A2230] Lisdexamfetamine is the first chemically formulated prodrug stimulant [A40246] and was first approved by the FDA in April 2008.[A2230] It was also approved by Health Canada in February 2009.

    Products: VYVANSE® 50 MG CAPSULAS, VYVANSE CAPSULES 50 mg
  8. Drug

    Ceftazidime

    go.drugbank.com/drugs/DB00438
    ApprovedInvestigational

    [L32935] Ceftazidime was approved by the FDA on July 19, 1985, and is currently available either alone or in combination with the non-β-lactam β-lactamase inhibitor [avibactam] to treat a variety of … [A232920] β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis, loss of cell integrity, and ultimately

    Mixtures: CEFAZIME FOR INJECTION 1 g/vial, ZAVİCEFTA 2 G/0.5 G İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 10 ADETCategories: Heterocyclic Compounds, 2-Ring
  9. Drug

    Pazopanib

    go.drugbank.com/drugs/DB06589
    ApprovedInvestigational

    Pazopanib is a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. It is developed by GlaxoSmithKline and was FDA approved on October 19, 2009.

    Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: VOTRIENT® 200 MG, VOTRIENT® 400 MG
  10. Drug

    Shea butter

    go.drugbank.com/drugs/DB14311
    Approved

    Shea butter is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Products: EM Shea Butter Cream