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Hydrocortisone
go.drugbank.com/drugs/DB00741ApprovedInvestigationalVet approved[L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone. … Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex.[A188387] Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions.
Mixtures: Oti Rx, DESYN-NCategories: Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use, Corticosteroids for Systemic UseFentanyl
go.drugbank.com/drugs/DB00813ApprovedIllicitInvestigationalVet approvedFentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia. … [A179542] Because of these characteristics, fentanyl is commonly used to treat chronic cancer pain or in anesthesia.
Mixtures: Innovar InjCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeDulaglutide
go.drugbank.com/drugs/DB09045ApprovedInvestigational[A236070] Dulaglutide was initially approved by the FDA in 2014, and in February 2020 was approved for use in patients with T2DM and multiple cardiovascular risk factors for the prevention of cardiovascular … therapy to diet and exercise in the management of 2 diabetes (T2DM).
Categories: Drugs Used in DiabetesProducts: Trulicity 1.5mg solution for injection in pre-filled pen, Trulicity 0.75mg solution for injection in pre-filled penEpirubicin
go.drugbank.com/drugs/DB00445ApprovedInvestigationalAn anthracycline which is the 4'-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.
Categories: Topoisomerase II InhibitorsProducts: EPIROL Epirubicin Hydrochloride Powder for Solution for Injection 10mg, EPIROL Epirubicin Hydrochloride Powder for Solution for Injection 50mgBotulinum toxin type A
go.drugbank.com/drugs/DB00083ApprovedInvestigationalIn 2002, botulinum toxin A, also known as onabotulinumtoxinA or Botox, was the first type A botulism toxin to be introduced into the market for cosmetic use. … [A231819,L32569] A popular use for Botox is the treatment of facial wrinkles and lines, however, there are many uses for the botulinum toxin A in the treatment of dystonia, incontinence, migraine, blepharospasm
Products: BOTOX (BOTULINUM TOXIN TYPE A) IM INJECTION, XEOMIN powder for solution for injection 100 LD50 unitsDexpanthenol
go.drugbank.com/drugs/DB09357ApprovedInvestigationalDexpanthenol is enzymatically cleaved to form pantothenic acid, which is an essential component of Coenzyme A, which acts as a cofactor in many enzymatic reactions that are important for protein metabolism … Due to its good penetration and high local concentrations, dexpanthanol is used in many topical products, such as ointments and lotions for treatment of dermatological conditions to relieve itching or
Mixtures: Venobene - Salbe, TAMIPOOL FOR INJECTIONCategories: Preparations for Treatment of Wounds and UlcersAmmonium chloride
go.drugbank.com/drugs/DB06767ApprovedInvestigationalVet approvedAmmonium chloride is an inorganic compound with the formula NH4Cl. It is highly soluble in water producing mildly acidic solutions.
Mixtures: NO- TOC JARABE, Bronchodex Fort-DM SyrProducts: AVIVA Sports Smelling Salts for Athletes, Acidax Inj 0.9% USPPotassium hydroxide
go.drugbank.com/drugs/DB11153ApprovedRecently, it has been studied for efficacy and tolerability in the treatment of warts. … It was determined that topical KOH solution was found to be a safe and effective treatment of plane warts [L1941].
Mixtures: Nutriflex Peri Solution for Infusion, Vamin NCategories: Compounds used in a research, industrial, or household setting, Potassium SaltPegaspargase
go.drugbank.com/drugs/DB00059ApprovedInvestigational[A255912,A255917] In February 1994, pegaspargase was approved by the FDA for the treatment of ALL in patients with hypersensitivity to native forms of L-asparaginase.[A255927] … [A103,A255912,L44667] Pegaspargase has the same mechanism of action as [L-asparaginase] derived from _Escherichia coli_, a previously developed enzyme used for the treatment of acute lymphoblastic
Categories: Compounds used in a research, industrial, or household settingProducts: ONCASPAR POWDER FOR SOLUTION FOR INJECTION/INFUSION 750 U/ML, Oncaspar 750 U/ml powder for solution for injection/infusionDaptomycin
go.drugbank.com/drugs/DB00080ApprovedInvestigational[A231384] Early work on developing daptomycin was abandoned due to observed myopathy but was resumed in 1997 when Cubist Pharmaceuticals Inc. licensed daptomycin; it was found that a once-daily dosing … [A231374, L32534] Daptomycin was first discovered in the early 1980s by researchers at Eli Lilly in soil samples from Mount Ararat in Turkey.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: Daptomycin for Injection RF, Daptomycin in Sodium Chloride