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Levosimendan
go.drugbank.com/drugs/DB00922ApprovedInvestigationalWithdrawnLevosimendan increases calcium sensitivity to myocytes by binding to troponin C in a calcium dependent manner. This increases contractility without raising calcium levels. … It also relaxes vascular smooth muscle by opening adenosine triphosphate sensitive potassium channels. Levosimendan is used to manage acutely decompensated congestive heart failure.
Categories: Compounds used in a research, industrial, or household settingProducts: SIMDAX 2.5 MG/ML CONCENTRATE FOR SOLUTION FOR INFUSION, Simdax 2.5 mg/ml concentrate for solution for infusion.Tozinameran
go.drugbank.com/drugs/DB15696ApprovedInvestigational[A225386] Comirnaty was granted a EUA in the UK on December 2, 2020,[L26676] and in Canada on December 9, 2020[L26671] for active immunization against SARS-CoV-2. … from one individual to another.
Products: Comirnaty 3mcg Concentrate for Dispersion for Injection, Comirnaty Omicron XBB.1.5 10 micrograms/dose Dispersion for InjectionVon Willebrand factor human
go.drugbank.com/drugs/DB13133ApprovedInvestigational[L1878] A recombinant form of vWF, [vonicog alfa], is also available to enhance production and avoid the theoretical risk of pathogen transmission from plasma donors.[A32262] … It was first approved by the FDA in 2015.
Mixtures: VONCENTO 1000 UI/ 2400 UI, Haemate P Powder and solvent for solution for injection or infusionProducts: IMMUNATE 50 IU/ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION, IMMUNATE 100 IU/ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTIONStyphnolobium japonicum flower bud
go.drugbank.com/drugs/DB14294InvestigationalStyphnolobium japonicum flower bud is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Synonyms: Huai Flower Bud, Huaihua (Flower Bud)Products: BARAMO for O ily Scalp, BARAMO for Normal ScalpAluminum chlorohydrate
go.drugbank.com/drugs/DB11573ApprovedIt is included up to 25% in over-the-counter hygiene products as an active antiperspirant agent.
Categories: Drugs for Treatment of Bone DiseasesProducts: Dove Men plus Care Minerals and Sage Dry Antiperspirant, Roll-on Antiperspirant for MenMeropenem
go.drugbank.com/drugs/DB00760ApprovedInvestigationalIn August 2017, a combination antibacterial therapy under the market name vabomere was approved for treatment of adult patients with complicated urinary tract infections (cUTI). … The treatment aims to resolve infection-related symptoms and achieve negative urine culture, where the infections are proven or strongly suspected to be caused by susceptible bacteria.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: Merozan 500mg powder for solution for injection or infusion, Pospenem Powder for Solution for Injection 1gRamucirumab
go.drugbank.com/drugs/DB05578ApprovedInvestigationalRamucirumab is indicated for us in advanced gastric or gastro-esophageal junction adenocarcinoma as a single agent or in combination with paclitaxel after prior fluoropyrimidine- or platinum-containing … In contrast to other agents directed against VEGFR-2, ramucirumab binds a specific epitope on the extracellular domain of VEGFR-2, thereby blocking all VEGF ligands from binding to it.
Products: CYRAMZA CONCENTRATE FOR SOLUTION FOR INFUSION 100MG/10ML, CYRAMZA CONCENTRATE FOR SOLUTION FOR INFUSION 500MG/50MLFexofenadine
go.drugbank.com/drugs/DB00950ApprovedInvestigational[L4269] It is selective for the H<sub>1</sub> receptor, carries little-to-no activity at off-targets, and does not cross the blood-brain barrier[L10779] - this is in contrast to previous first-generation
Categories: Antihistamines for Systemic UseProducts: Up and Up Allergy Relief, Up and Up Non Drowsy Allergy ReliefCarbamide peroxide
go.drugbank.com/drugs/DB11129ApprovedInvestigationalSome adverse effects of carbamide peroxide as a dental bleaching agent include dentin sensitivity and/or gingival irritation led by unstable and reactive H+ free radicals and low pH from prolonged use. … The FDA considers carbamide peroxide to be safe in oral mucosal injury drug products as an oral wound healing agent, although there is insufficient data to establish general recognition of the effectiveness
Categories: Compounds used in a research, industrial, or household settingProducts: Ear Wax Removal Drops Up and UpEpoprostenol
go.drugbank.com/drugs/DB01240ApprovedInvestigationalIt is biosynthesized enzymatically from prostaglandin endoperoxides in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension.
Products: VELETRI POWDER FOR SOLUTION FOR INFUSION 0.5MG/VIAL, VELETRI POWDER FOR SOLUTION FOR INFUSION 1.5MG/VIAL