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Agalsidase alfa
go.drugbank.com/drugs/DB15874ApprovedInvestigationalAgalsidase alfa is a recombinant human α-galactosidase A similar to agalsidase beta. While patients generally do not experience a clinically significant difference in outcomes between the two drugs, some patients may experience greater b...
Tranexamic acid
go.drugbank.com/drugs/DB00302ApprovedInvestigationalTranexamic acid is a synthetic derivative of lysine used as an antifibrinolytic in the treatment and prevention of major bleeding. It possesses a similar mechanism of action to aminocaproic acid but is approximately 10-fold more potent. ...
Dinoprost tromethamine
go.drugbank.com/drugs/DB01160ApprovedVet approvedWithdrawnThe tromethamine (THAM) salt of the naturally occurring prostaglandin F2 alpha, dinoprost tromethamine occurs as a white to off-white, very hygroscopic, crystalline powder. Dinoprost tromethamine may also be known as dinoprost trometamol...
Phenazopyridine
go.drugbank.com/drugs/DB01438ApprovedInvestigationalPhenazopyridine, also known as Pyridium, is a urinary tract analgesic used for the short-term management of urinary tract irritation and its associated unpleasant symptoms such as burning and pain during urination. In the USA, this drug ...
Lanreotide
go.drugbank.com/drugs/DB06791ApprovedInvestigationalLanreotide is a drug employed in the management of acromegaly (a hormonal condition caused by excess growth hormone) in addition to symptoms caused by neuroendocrine tumors, especially carcinoid syndrome. This drug is a long-acting analo...
Calcium threonate
go.drugbank.com/drugs/DB11168ApprovedWithdrawnCalcium threonate is a calcium salt of threnoic acid and a novel drug developed for the treatment of osteoporosis and as a calcium supplement . It is found in dietary supplements as a source of L-threonate used in the treatment of calciu...
Carbamide peroxide
go.drugbank.com/drugs/DB11129ApprovedInvestigationalIt may also alter enamel surface morphology via enamel mineral loss and surface roughening [A32336].
Tislelizumab
go.drugbank.com/drugs/DB14922ApprovedInvestigationalIt was engineered to have a nullified Fc portion, thus minimizing binding to FcγR on macrophages and limiting treatment resistance via antibody-dependent phagocytosis.
Eladocagene exuparvovec
go.drugbank.com/drugs/DB16780ApprovedInvestigationalapproval of this gene therapy, the treatment options for patients with AADC deficiency were limited to attempts to increase monoamine neurotransmitter production, decrease neurotransmitter catabolism via
Lunsotogene parvec
go.drugbank.com/drugs/DB18278ApprovedInvestigational[L56137] It acts by delivering functional copies of the human _OTOF_ gene specifically to inner hair cells via an engineered hair-cell-specific Myo15 promoter, which restores essential synaptic transmission