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Displaying results 351 - 360 of 10000 in total
  1. Drug

    Aceclofenac

    go.drugbank.com/drugs/DB06736
    Approved

    It is a more commonly prescribed drug in Europe. … In 1991, aceclofenac was developed as an analog of a commonly prescribed NSAID, [DB00586], via chemical modification in effort to improve the gastrointestinal tolerability of the drug.

    Products: ACECLOFENAC EG
  2. Drug

    Almotriptan

    go.drugbank.com/drugs/DB00918
    Approved

    Almotriptan is a triptan drug for the treatment of migraine headaches. Almotriptan is in a class of medications called selective serotonin receptor agonists. … It works by narrowing blood vessels in the brain, stopping pain signals from being sent to the brain, and stopping the release of certain natural substances that cause pain, nausea, and other symptoms

    Categories: Monoamine Oxidase A SubstratesProducts: ALMOTRIPTAN EG
  3. Drug

    Phentermine

    go.drugbank.com/drugs/DB00191
    ApprovedIllicitInvestigational

    Phentermine is a sympathomimetic amine anorectic agent and it was introduced in 1959 as part of an anti-obesity combination drug. … [A174376, T403] Later on, phentermine was approved alone and in combination with topiramate in 2012 as a new alternative that required lower doses of phentermine to obtain the desired effect.[A174373]

    Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesProducts: Phentermine Resin ER
  4. Drug

    Manidipine

    go.drugbank.com/drugs/DB09238
    ApprovedInvestigationalWithdrawn

    Manidipine (INN) is a calcium channel blocker (dihydropyridine type) that is used clinically as an antihypertensive. … It is selective for vasculature and does not produce effects on the heart at clinically relevant dosages.

    Products: MANIDIPINA EG
  5. Drug

    Felodipine

    go.drugbank.com/drugs/DB01023
    Approved

    It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. … In addition to binding to L-type calcium channels, felodipine binds to a number of calcium-binding proteins, exhibits competitive antagonism of the mineralcorticoid receptor, inhibits the activity of calmodulin-dependent

    International brands: Felodur ER, Plendil ERProducts: PLENDIL 2.5MG ER TABLET, PLENDIL 5 ER TABLETS (9MM)
  6. Drug

    Zinc oxide

    go.drugbank.com/drugs/DB09321
    ApprovedInvestigational

    Zinc oxide is an inorganic compound used in a number of manufacturing processes. … It is also widely used to treat a variety of other skin conditions, in products such as baby powder and barrier creams to treat diaper rashes, calamine cream, anti-dandruff shampoos, and antiseptic ointments

    Mixtures: La Roche Posay Laboratoire Dermatologique Anthelios 50 Mineral Ultra Light Sunscreen, La Roche Posay Laboratoire Dermatologique Anthelios HA Mineral Broad Spectrum SPF 30 Daily Moisturizing SunscreenCategories: Compounds used in a research, industrial, or household setting
  7. Drug

    Eribulin

    go.drugbank.com/drugs/DB08871
    ApprovedInvestigational

    Eribulin is also being investigated for use in the treatment of advanced solid tumors [A7439]. … Eribulin is a microtubule inhibitor indicated for the treatment of patients with metastatic breast cancer who have previously received at least two chemotherapeutic regimens for the treatment of metastatic

    Products: ERIBULINA EG
  8. Drug

    Tramadol

    go.drugbank.com/drugs/DB00193
    ApprovedInvestigational

    Tramadol differs from other traditional opioid medications in that it doesn't just act as a μ-opioid agonist, but also affects monoamines by modulating the effects of neurotransmitters involved in the … If used in higher doses, or with other opioids, there is a dose-related risk of overdose, respiratory depression, and death.

    Mixtures: ORDEGAN, TRAMADOLO E PARACETAMOLO EGProducts: Ultram ER, Tramadol ER
  9. Drug

    Alprazolam

    go.drugbank.com/drugs/DB00404
    ApprovedIllicitInvestigational

    [A18125] Alprazolam was given FDA approval on October 16, 1981.[L6148] … Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders.

    Synonyms: 8-Chloro-1-methyl-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepineProducts: Alprazolam ER, ALPRAZOLAM EG
  10. Drug

    Orphenadrine

    go.drugbank.com/drugs/DB01173
    ApprovedInvestigational

    A muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.

    Synonyms: N,N-Dimethyl-2-(alpha-2-tolylbenzoyloxy)ethylamine, N,N-dimethyl-2-(phenyl(o-tolyl)methoxy)ethanamineProducts: Orphenadrine Citrate ER