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Dapsone
go.drugbank.com/drugs/DB00250ApprovedInvestigationalIt is also used with pyrimethamine in the treatment of malaria. (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8) … Its mechanism of action is probably similar to that of the sulfonamides which involves inhibition of folic acid synthesis in susceptible organisms.
Products: Dapsone 100mg, Avlosulfon Tab 100mgBisacodyl
go.drugbank.com/drugs/DB09020ApprovedInvestigational[A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956[L33045] but has been used as a laxative since 1952.[A233300]
Products: Apo-bisacodyl Sup 10mg, PRICOLAX SUPPOSITORIES 10MGRavulizumab
go.drugbank.com/drugs/DB11580ApprovedInvestigational[A244465] Ravulizumab was first approved by the FDA on December 21, 2018, for the treatment of paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome in children and adults. … It is a humanized monoclonal IgG2/4 kappa antibody produced in Chinese hamster ovary (CHO) cells.
Products: ULTOMIRIS ® RAVULIZUMAB 100MG/ML., Ultomiris 100mg/mL Concentrate For Solution For InfusionIsavuconazonium
go.drugbank.com/drugs/DB06636ApprovedInvestigationalDue to low solubility in water of isavuconazole on its own, the isovuconazonium formulation is favorable as it has high solubility in water and allows for intravenous administration. … [A6913,A6914,A262706] On December 08, 2023, the FDA approved the expanded use of isovuconazonium in pediatric patients for the same indications.[L49251]
Products: Cresemba 100mg Capsule, CRESEMBA CAPSULES 100MGMagnesium carbonate
go.drugbank.com/drugs/DB09481ApprovedMagnesium carbonate, also known as magnesite, is a common over the counter remedy for heartburn and upset stomach caused by overproduction of acid in the stomach [FDA Label].
Mixtures: Sintra-ES, Calcium Et Magnesium TabCategories: Compounds used in a research, industrial, or household settingMinocycline
go.drugbank.com/drugs/DB01017ApprovedInvestigationalMinocycline was first described in the literacture in 1966.[A190681] It is a second generation tetracycline antibiotic that is active against gram-negative and gram-positive bacteria. … [A190723] Minocycline was granted FDA approval on 30 June 1971.[L11695]
Products: Enca 100mg, Minocin Cap 100mgSimvastatin
go.drugbank.com/drugs/DB00641ApprovedInvestigational[A181087, A181406] Simvastatin and other drugs from the statin class of medications including [atorvastatin], [pravastatin], [rosuvastatin], [fluvastatin], and [lovastatin] are considered first-line … clinical studies to result in a 45.8% to 54.6% decrease in LDL cholesterol levels, while simvastatin has been found to have an average decrease in LDL-C of ~35%.
Mixtures: VALCORE TABLET 10MG/10MG, VYTORIN ® 10/10MGProducts: SIMVASTATINA EG, STATIN 10MGLinagliptin
go.drugbank.com/drugs/DB08882ApprovedInvestigationalLinagliptin was approved by the FDA on May 2, 2011[L9557]. … Linagliptin differs from other DPP-4 inhibitors in that it has a non-linear pharmacokinetic profile, is not primarily eliminated by the renal system, and obeys concentration dependant protein binding[A37050
Mixtures: Glyxambi Film-Coated Tablets 10mg/5mg, TRAJENTA DUO FILM-COATED TABLETS 2.5MG / 1000MGCategories: Drugs Used in DiabetesAzathioprine
go.drugbank.com/drugs/DB00993ApprovedInvestigationalAzathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic … [L11214] Azathiprine was granted FDA approval on 20 March 1968.[L11214]
Products: AZAFALK 100MG, Imuran Inj 100mgClotrimazole
go.drugbank.com/drugs/DB00257ApprovedInvestigationalVet approvedClotrimazole's antimycotic properties were discovered in the late 1960s [A174094]. … It is available in various preparations, including creams, pessaries, and troche formulations (slowly dissolving tablets).
Mixtures: CLINDAMICINA / CLOTRIMAZOL 100MG/200MG, MYKOFUNGIN 3 200MG+10MG/GProducts: PRO-EX Anti Fungal, Myclo Tab 100mg