Search

Displaying results 3591 - 3600 of 10000 in total
  1. Drug

    Vincristine

    go.drugbank.com/drugs/DB00541
    ApprovedInvestigational

    Vincristine is an antitumor vinca alkaloid isolated from Vinca Rosea. … It is marketed under several brand names, many of which have different formulations such as Marqibo (liposomal injection) and Vincasar.

    Mixtures: MEODEX®, MEODEX®Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index
  2. Drug

    Thymoquinone

    go.drugbank.com/drugs/DB16447
    Investigational

    Thymoquinone is a natural compound with widespread protective effects, including anti-oxidative, anti-inflammatory, immunomodulatory, anti-cancer, and anti-microbial.

    Synonyms: 2-Isopropyl-5-methyl-p-benzoquinone, p-Cymene-2,5-dioneCategories: Experimental Unapproved Treatments for COVID-19
  3. Drug

    NS-3728

    go.drugbank.com/drugs/DB05835
    Experimental

    NS3728 is an orally active chloride channel blocker for the treatment of cancer.

    Synonyms: N-[4-bromo-2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]-N'-[3,5-bis(trifluoromethyl)phenyl]urea
  4. Drug

    TTX-siPDL1

    go.drugbank.com/drugs/DB18550
    Experimental

    TTX-siPDL1 is an siRNA-based modulator of programmed death-ligand 1.

    Synonyms: Magnetic nanocarrier-conjugated small interfering RNA against programmed death ligand 1
  5. Drug

    TC-2216

    go.drugbank.com/drugs/DB06044
    Investigational

    TC-2216 is an investigational novel small molecule that is being developed as an oral treatment for depression and anxiety disorders.

    Synonyms: 1,7-DIAZASPIRO(4.4)NONANE, 7-(3-PYRIDINYL)-, HYDROCHLORIDE (1:3)
  6. Drug

    Pyrifazimine

    go.drugbank.com/drugs/DB18898
    Investigational

    Pyrifazimine is under investigation in clinical trial NCT04670120 (Early Bactericidal Activity Safety Pulmonary Tuberculosis Pyrifazimine (TBI-166)).

    Synonyms: 2-PHENAZINAMINE, 3,5-DIHYDRO-3-((4-METHOXYCYCLOHEXYL)IMINO)-N-(2-METHOXY-3-PYRIDINYL)-5-(4-(TRIFLUOROMETHOXY)PHENYL)-
  7. Drug

    INO-4995

    go.drugbank.com/drugs/DB17834
    Experimental

    INO-4995 is an inositol tetrakisphosphate analog being investigated for Cystic Fibrosis.[A259781]

    Synonyms: 2-O-butyryl-1-O-octyl-myo-Inositol 3,4,5,6-tetrakisphosphate octakis(propionoxymethyl)ester
  8. Drug

    INO-1001

    go.drugbank.com/drugs/DB05549
    Investigational

    Synonyms: (9-(N-(3-Morpholinopropyl)-sulfonyl)-5,6-dihydro-5-oxo-11-H-indeno (1,2-C) isoquinoline methanesulfonic acidCategories: Heterocyclic Compounds, 2-Ring
  9. Drug

    Seliciclib

    go.drugbank.com/drugs/DB06195
    Investigational

    R-roscovitine (Seliciclib or CYC202) is a cyclin-dependent kinase (CDK) inhibitor that preferentially inhibits multiple enzyme targets including CDK2, CDK7 and CDK9, which alter the growth phase of treated

    Synonyms: 2-(R)-(1-ethyl-2-hydroxyethylamino)-6-benzylamino-9-isopropylpurine, R-roscovitineCategories: Heterocyclic Compounds, 2-Ring
  10. Drug

    8-azaguanine

    go.drugbank.com/drugs/DB01667
    Experimental

    8-azaguanine is one of the early purine analogs showing antineoplastic activity. It functions as an antimetabolite and is easily incorporated into ribonucleic acids.

    Synonyms: 8 AG, 3-amino-2,4,7,8,9-pentazabicyclo[4.3.0]nona-1,3,6-trien-5-oneCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-Ring