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mRNA-1010
go.drugbank.com/drugs/DB22484Approvedbenefit to be confirmed in a postmarketing trial. … [L64058] The FDA approved mFLUSIVA on August 5, 2026 for active immunization against influenza in adults 50 years of age and older, making it the first mRNA-based influenza vaccine approved in the United
Propylthiouracil
go.drugbank.com/drugs/DB00550ApprovedIt is used in the treatment of hyperthyroidism. (From Martindale, The Extra Pharmacopeoia, 30th ed, p534) … A thiourea antithyroid agent. Propythiouracil inhibits the synthesis of thyroxine and inhibits the peripheral conversion of throxine to tri-iodothyronine.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 2-Mercapto-6-propyl-4-pyrimidone, 2-Mercapto-6-propylpyrimid-4-oneTolmetin
go.drugbank.com/drugs/DB00500ApprovedA non-steroidal anti-inflammatory agent (anti-inflammatory agents, NON-steroidal) similar in mode of action to indomethacin.
Synonyms: 1-Methyl-5-p-toluoylpyrrole-2-acetic acid, 1-Methyl-5-(4-methylbenzoyl)-pyrrole-2-acetic acidCategories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 1-RingCholine C-11
go.drugbank.com/drugs/DB09563ApprovedCholine C 11 Injection is a radioactive diagnostic agent for positron emission tomography (PET) imaging of pat ients with suspected prostate cancer recurrence and non-informative bone scintigraphy, computerized
Synonyms: Choline C-11, (11)C-cholineProducts: Choline C 11Flavoxate
go.drugbank.com/drugs/DB01148ApprovedA drug that has been used in various urinary syndromes and as an antispasmodic. Its therapeutic usefulness and its mechanism of action are not clear. … It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a muscarinic antagonist. [PubChem]
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: 2-(1-piperidinyl)ethyl 3-methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylate, 2-piperidinoethyl 3-methyl-4-oxo-2-phenyl-4H-1-benzopyran-8-carboxylateZileuton
go.drugbank.com/drugs/DB00744ApprovedWithdrawnSpecifically, it inhibits leukotriene LTB4, LTC4, LTD4, and LTE4 formation. Both the R(+) and S(-) enantiomers are pharmacologically active as 5-lipoxygenase inhibitors in in vitro systems. … These effects contribute to inflammation, edema, mucus secretion, and bronchoconstriction in the airways of asthmatic patients.
Synonyms: N-(1-Benzo(b)thien-2-ylethyl)-N-hydroxyurea, N-[1-(benzo[b]thiophen-2-yl)ethyl]-N-hydroxyureaCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsHyaluronidase (human recombinant)
go.drugbank.com/drugs/DB06205ApprovedInvestigational[A199047] Hyaluronidase was first used in prescription products in the United States on 5 May 2004.[L13338] … [L13338] The action of hyaluronidase was first described in 1936, and named in 1939.
Trichloroethylene
go.drugbank.com/drugs/DB13323ApprovedTrichloroethylene is a halocarbon commonly used as an industrial solvent, not to be confused with the similar 1,1,1-trichloroethane, also known as chlorothene. … It has been sold under a variety of trade names including Trimar and Trilene and used as a volatile anesthetic and as an inhaled obstetrical analgesic.
Synonyms: 1,1-dichloro-2-chloroethyleneCategories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 SubstratesEnmetazobactam
go.drugbank.com/drugs/DB18716ApprovedInvestigationalEnmetazobactam is a penicillanic acid sulfone extended-spectrum beta (β)-lactamase (ESBL) inhibitor. … [A263266] Because ESBL enzymes can hydrolyze important antibiotics such as penicillins, broad-spectrum cephalosporins and monobactams, ESBL-producing bacteria poses challenges in the treatment of serious
Synonyms: (2s,3s,5r)-3-methyl-3-((3-methyltriazol-3-ium-1-yl)methyl)-4,4,7-trioxo-4^6-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate, 1h-1,2,3-triazolium, 3-(((2s,3s,5r)-2-carboxy-3-methyl-4,4-dioxido-7-oxo-4-thia-1-azabicyclo(3.2.0)hept-3-yl)methyl)-1-methyl-, inner saltCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP2E1 InhibitorsTechnetium Tc-99m tilmanocept
go.drugbank.com/drugs/DB09266ApprovedOnce reconstituted and labelled, technetium Tc99m tilmanocept is intended to be injected in close proximity to the tumor being diagnosed and employed in preoperative gamma detection imaging in combination … However, as nodal micrometastasis in breast cancer may not be associated with significant changes in survival, it is also important to identify clinically node-negative patients [A32170].