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SQ-109
go.drugbank.com/drugs/DB05186InvestigationalSQ-109 is an orally active, small molecule antibiotic for treatment of pulmonary TB.
Pimagedine
go.drugbank.com/drugs/DB05383InvestigationalIt is an advanced glycation end product inhibitor which manages diabetic nephropathy, either alone or in combination with other therapies.
Vicriviroc
go.drugbank.com/drugs/DB06652InvestigationalVicriviroc, also known as SCH 417690 and SCH-D, is currently in clinical trials for the management of HIV-1.
BF-1
go.drugbank.com/drugs/DB06029ExperimentalBF-1 is an investigational 5-HT2B receptor antagonist developed for the prophylaxis of Migraines.
Delgocitinib
go.drugbank.com/drugs/DB16133ApprovedInvestigationalDelgocitinib is a pan-Janus kinase (JAK) inhibitor. After the first global approval in Japan,[A264693] delgocitinib was also approved by the European Commission on September 23, 2024.
Unoprostone
go.drugbank.com/drugs/DB06826ApprovedWithdrawnUnoprostone isopropyl is a prostaglandin analogue. Ophthalmic Solution 0.15% is a synthetic docosanoid.
Narsoplimab
go.drugbank.com/drugs/DB16418ApprovedInvestigational[A241030, A241040] Narsoplimab (OMS721), a human IgG4λ anti-MASP-2 antibody, is under consideration as a treatment for hematopoietic stem cell transplant-associated TMA (HSCT-TMA/TA-TMA) and IgA nephropathy … [A241030] Evidence increasingly points to a role for the complement system in TMA.
Temoporfin
go.drugbank.com/drugs/DB11630ApprovedTemoporfin is a photosensitizing agent used in the treatment of squamous cell carcinoma of the head and neck [FDA Label].
Synonyms: m-THPC, 2,3-dihydro-5,10,15,20-tetra(m-hydroxyphenyl)porphyrinArtesunate
go.drugbank.com/drugs/DB09274ApprovedInvestigational[L890] Artesunate was developed out of a need for a more hydrophilic derivative of [artemisinin].[A203948] Artesunate was granted FDA approval on 26 May 2020.[L14099] … [L14099] The World Health Organization recommends artesunate as first line treatment for severe malaria.
Synonyms: ASAnthrax immune globulin human
go.drugbank.com/drugs/DB09057ApprovedInvestigationalAvailable as the product Anthrasil (FDA), the result is a solution for slow IV infusion containing polyclonal antibodies that bind the protective antigen (PA) component of Bacillus anthracis lethal and … Anthrax immune globulin is a human antibody given with antibiotics for the treatment of anthrax.