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Displaying results 3611 - 3620 of 10000 in total
  1. Drug

    L-arginine

    go.drugbank.com/drugs/DB17289
    ApprovedInvestigationalNutraceutical

    Mixtures: Vamin N, Aminosyn II In Dextrose Injection
  2. Drug

    Heterotheca inuloides flower

    go.drugbank.com/drugs/DB14331
    Approved

    Heterotheca inuloides flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Mixtures: Arnica De LA Abuela
  3. Drug

    Oxyphenisatin acetate

    go.drugbank.com/drugs/DB14627
    ApprovedWithdrawn

    Oxyphenisatin acetate is the pro-drug of [oxyphenisatin] (3,3-bis(4-hydroxyphenyl)-1H-indol-2-one). The FDA withdrew its approval for the use of oxyphenisatin acetate due to safety reasons.[L43942]

  4. Drug

    Enbucrilate

    go.drugbank.com/drugs/DB12358
    Investigational

    Enbucrilate is under investigation in clinical trial NCT02468206 (Secondary Prophylaxis of Gastric Variceal Bleed).

    Categories: Compounds used in a research, industrial, or household settingSynonyms: N-butyl cyanoacrylate, N-butyl-2-cyanoacrylate
  5. Drug

    Ethotoin

    go.drugbank.com/drugs/DB00754
    Approved

    Ethotoin exerts an antiepileptic effect without causing general central nervous system depression. The mechanism of action is probably very similar to that of phenytoin. … The latter drug appears to stabilize rather than to raise the normal seizure threshold, and to prevent the spread of seizure activity rather than to abolish the primary focus of seizure discharges.

  6. Drug

    Morniflumate

    go.drugbank.com/drugs/DB09285
    Investigational

    In one study, post morniflumate ingestion, physical examination and clinical symptoms of those with bronchitis showed improvement [A7889]. … Morniflumate is a non-steroidal anti-inflammatory drug with antipyretic properties. It is the morpholinoethyl ester of niflumic acid [L1496].

    Categories: Anti-Inflammatory Agents, Non-Steroidal, Antiinflammatory and Antirheumatic Products, Non-Steroids
  7. Drug

    Flucloxacillin

    go.drugbank.com/drugs/DB00301
    ApprovedInvestigationalWithdrawn

    Antibiotic analog of [cloxacillin].

    Categories: combinations of penicillins
  8. Drug

    Artemether

    go.drugbank.com/drugs/DB06697
    ApprovedInvestigational

    This combination therapy exerts its effects against the erythrocytic stages of <i>Plasmodium spp. … Artemether is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with lumefantrine for improved efficacy.

  9. Drug

    Parecoxib

    go.drugbank.com/drugs/DB08439
    ApprovedInvestigational

    A letter of non-approval for parecoxib was issued by the FDA in 2005. … Parecoxib is a water-soluble and injectable prodrug of valdecoxib. It is marketed as Dynastat in the European Union.

    Synonyms: N-((p-(5-methyl-3-phenyl-4-isoxazolyl)phenyl)sulfonyl)propionamideCategories: Analgesics, Non-Narcotic, Anti-Inflammatory Agents, Non-Steroidal
  10. Drug

    Defactinib

    go.drugbank.com/drugs/DB12282
    ApprovedInvestigational

    Defactinib is a small molecule kinase inhibitor targeted against focal adhesion kinase (FAK) and proline-rich tyrosine kinase-2 (Pyk2), the two members of the FAK family of nonreceptor tyrosine kinases … resistance mechanism to MAPK inhibitors, facilitating tumor cell proliferation and survival in the absence of MAPK signaling.

    Synonyms: N-methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]benzamide