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Pevonedistat
go.drugbank.com/drugs/DB11759InvestigationalPevonedistat has been used in trials studying the treatment of Lymphoma, Solid Tumors, Multiple Myeloma, Hodgkin Lymphoma, and Metastatic Melanoma, among others.
Categories: Heterocyclic Compounds, 1-RingItacitinib
go.drugbank.com/drugs/DB12154InvestigationalItacitinib has been used in trials studying the treatment of Melanoma, Carcinoma, Metastatic Cancer, Endometrial Cancer, and B-cell Malignancies, among others.
Categories: Heterocyclic Compounds, 1-RingAdavosertib
go.drugbank.com/drugs/DB11740InvestigationalMK-1775 has been used in trials studying the treatment of LYMPHOMA, Neoplasms, Ovarian Cancer, Tongue Carcinoma, and Adult Glioblastoma, among others.
Categories: Heterocyclic Compounds, 1-RingVerinurad
go.drugbank.com/drugs/DB11873InvestigationalVerinurad has been used in trials studying the basic science and treatment of Gout, Gout and Hyperuricemia, and Gout and Asymptomatic Hyperuricemia.
Categories: Heterocyclic Compounds, 1-RingRST-001
go.drugbank.com/drugs/DB17843InvestigationalRST-001 is a non-replicating recombinant adeno-associated virus vector containing a fragment of the gene encoding channel rhodopsin-2 protein.
AAV-dXIAP
go.drugbank.com/drugs/DB17880ExperimentalAAV-dXIAP is a recombinant adeno-associated virus-encoded gene for X-linked mammalian inhibitor of apoptosis protein (XIAP) developed by Neurologix.
Ilginatinib
go.drugbank.com/drugs/DB12784InvestigationalNS-018 has been used in trials studying the treatment of Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, and Post-Essential Thrombocythemia Myelofibrosis.
Synonyms: (S)-N-(1-(4-FLUOROPHENYL)ETHYL)-4-(1-METHYL-1H-PYRAZOL-4-YL)-N'-(PYRAZIN-2-YL)PYRIDINE-2,6-DIAMINE, 2,6-PYRIDINEDIAMINE, N2-((1S)-1-(4-FLUOROPHENYL)ETHYL)-4-(1-METHYL-1H-PYRAZOL-4-YL)-N6-2-PYRAZINYL-PAC-1
go.drugbank.com/drugs/DB13048InvestigationalPAC-1 has been used in trials studying the treatment of Lymphoma, Melanoma, Solid Tumors, Breast Cancer, and Thoracic Cancers, among others.
Synonyms: PAC-1, Procaspase activating compound 1Carboxyamidotriazole
go.drugbank.com/drugs/DB11960InvestigationalCarboxyamidotriazole has been used in trials studying the treatment of Lymphoma, Lung Cancer, Breast Cancer, Kidney Cancer, and Ovarian Cancer, among others.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingLY-3023414
go.drugbank.com/drugs/DB12167InvestigationalLY3023414 has been used in trials studying the treatment of Neoplasm, Solid Tumor, COLON CANCER, BREAST CANCER, and Advanced Cancer, among others.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring