Pevonedistat

DB11759InvestigationalSmall molecule

Pevonedistat has been used in trials studying the treatment of Lymphoma, Solid Tumors, Multiple Myeloma, Hodgkin Lymphoma, and Metastatic Melanoma, among others.

Formula / weight: C₂₁H₂₅N₅O₄S · 443.519 g/mol (avg)
Code names: MLN-4924

Resolves to

Compound

UNIIS3AZD8D215CAS905579-51-3ChEMBLCHEMBL1231160ChEBI95028PubChem16720766

Structure

InChIKeyMPUQHZXIXSTTDU-QXGSTGNESA-NSMILES[H][C@]1(O)C[C@@]([H])(C[C@@]1([H])COS(N)(=O)=O)N1C=CC2=C(N[C@@]3([H])CCC4=CC=CC=C34)N=CN=C12

Targets

Q15843NEDD8Q8TBC4UBA3Q13564NAE1

What you can answer from here — as of September 12, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

39Clinical trialsPhase, status and sponsor resolved per trial

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with Pevonedistat, and which of those have an active Phase 3 trial?

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