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Etoricoxib
go.drugbank.com/drugs/DB01628ApprovedInvestigationalWithdrawnLike any other COX-2 selective inhibitor, Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme (COX-2) to reduce the generation of prostaglandins (PGs) from arachidonic acid.
Products: ETORICOXIB DOC GENERICI, ETORICOXIB GENERIC PARTNERSDesoxyribonuclease
go.drugbank.com/drugs/DB09551ApprovedInvestigationalThe enzyme's cofactor is reported to be magnesium (or manganese) ions, although the optimal concentration of the ion is independent of the enzyme concentration [A31251].
Nevadistinel
go.drugbank.com/drugs/DB21632InvestigationalThe usage of the INN stem '-stinel' in the name indicates that Nevadistinel is a N-methyl-D-aspartate (NMDA) receptor co-agonist. … Nevadistinel is under investigation in clinical trial NCT04148391 (NYX-458 in Subjects With Mild Cognitive Impairment or Mild Dementia Due to Parkinson's Disease or Lewy Body Dementia (Cognition, Memory
Astaxanthin
go.drugbank.com/drugs/DB06543InvestigationalAstaxanthin has shown to mediate anti-oxidant and anti-inflammatory actions. It may be found in fish feed or some animal food as a color additive. … It is classified as a xanthophyll but it is a carotenoid with no vitamin A activity. It is found in the majority of aquatic organisms with red pigment.
Papaverine
go.drugbank.com/drugs/DB01113ApprovedInvestigationalAn alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions.
International brands: Ro-PapavChromium picolinate
go.drugbank.com/drugs/DB11255ApprovedChromium ions are shown to regulate insulin by promoting glucose utilization and increasing the sensitivity of the insulin receptor [A27235].
Methscopolamine
go.drugbank.com/drugs/DB11315ApprovedThe oral tablets are used as an adjunct therapy for the treatment of peptic ulcer and is shown to be effective in decreasing the rate of recurrence of peptic ulcers as well as preventing complications.
Propolis wax
go.drugbank.com/drugs/DB11355ApprovedInvestigationalIt is often found in topical formulations used to soothe minor skin irritations.
Squalene
go.drugbank.com/drugs/DB11460ApprovedInvestigationalVet approvedWithdrawnIt is not susceptible to lipid peroxidation and provides skin protection.
Taurochenodeoxycholic acid
go.drugbank.com/drugs/DB08833ExperimentalIts physiologic function is to emulsify lipids such as cholesterol in the bile. … As a medication, taurochenodeoxycholic acid reduces cholesterol formation in the liver, and is likely used as a choleretic to increase the volume of bile secretion from the liver and as a cholagogue to