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Displaying results 3621 - 3630 of 7284 in total
  1. Target

    NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial

    go.drugbank.com/bio_entities/BE0000027
    TargetHumans

    May be the terminally assembled subunit of Complex I … Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.

    Synonyms: Complex I-9kD
  2. Target

    NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

    go.drugbank.com/bio_entities/BE0000754
    TargetHumans

    Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. … Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

    Synonyms: Complex I-B17.2
  3. Target

    Phospholipid-transporting ATPase ID

    go.drugbank.com/bio_entities/BE0013936
    TransporterHumans

    Catalytic component of P4-ATPase flippase complex, which catalyzes the hydrolysis of ATP coupled to the transport of phosphatidylcholine (PC) from the outer to the inner leaflet of the plasma membrane.

    Synonyms: P4-ATPase flippase complex alpha subunit ATP8B2
  4. Drug

    Eplontersen

    go.drugbank.com/drugs/DB16199
    ApprovedInvestigational

    +7) and the Norfolk Quality of Life Questionnaire-Diabetic Neuropathy (Norfolk QoL-DN) Score were observed. … It was previously investigated as a potential treatment for hereditary transthyretin-mediated amyloidosis.

  5. Drug

    Flotufolastat F-18

    go.drugbank.com/drugs/DB17851
    ApprovedInvestigational

    Flotufolastat F-18 is a diastereoisomer of <sup>18</sup>F-rhPSMA-7, and compared to the other diastereoisomers of this compound, flotufolastat F-18 has a faster clearance from blood pool, liver, and kidney … , and a high level of accumulation in tumors.

  6. Drug

    Voretigene neparvovec

    go.drugbank.com/drugs/DB13932
    ApprovedInvestigational

    [L1094] An adeno-associated virus is a small virus that infects humans and other primates. It is not pathogenic and it causes a very mild immune response. … [A31478] VN-rzyl was developed by Spark Therapeutics Inc. and FDA approved on December 19, 2017.[L1095]

  7. Drug

    Coagulation factor X human

    go.drugbank.com/drugs/DB13148
    ApprovedInvestigational

    It is a two-chain glycoprotein with the molecular weight of approximately 59 kDa [A31472]. … Coagulation Factor X is a vitamin K-dependent, liver-produced serine protease that serves as the first enzyme in the coagulation cascade to form fibrin.

    Mixtures: UMAN COMPLEX, UMAN COMPLEX
  8. Drug

    Inodiftagene vixteplasmid

    go.drugbank.com/drugs/DB16017
    Investigational

    Inodiftagene vixteplasmid is a plasmid DNA vector encoding the diphtheria toxin A (dT-a) gene under transcriptional regulation of the promoter region of the human H19 gene (an imprinted maternally expressed

    Synonyms: dT-A-H19, diphtheria-toxin-A-H19
  9. Drug

    Detirelix

    go.drugbank.com/drugs/DB19488
    Experimental

    Detirelix has a monoisotopic molecular weight of 1536.78 Da. … Detirelix is a small molecule drug. The usage of the INN stem '-relix' in the name indicates that Detirelix is a gonadotropin-releasing-hormone (GnRH) inhibitor.

  10. Drug

    Terdecamycin

    go.drugbank.com/drugs/DB19720
    Experimental

    Terdecamycin has a monoisotopic molecular weight of 585.31 Da. … Terdecamycin is a small molecule drug. The usage of the INN stem '-mycin' in the name indicates that Terdecamycin is a antibiotic, produced by Streptomyces strain.