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Ulimorelin
go.drugbank.com/drugs/DB12128InvestigationalUlimorelin is a novel small molecule ghrelin agonist being developed by Tranzyme Pharma as a first-in-class treatment for both POI and diabetic gastroparesis, serious medical conditions in which motility
Mercaptopurine
go.drugbank.com/drugs/DB01033ApprovedInvestigationalAn antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission...
Hydromorphone
go.drugbank.com/drugs/DB00327ApprovedIllicitInvestigationalHydromorphone is a pure opioid, a semi-synthetic hydrogenated ketone derivative of morphine that has been available clinically since 1920. Structurally, hydromorphone derived from morphine in the modification of the hydroxyl group in the...
Hyoscyamine
go.drugbank.com/drugs/DB00424ApprovedInvestigationalHyoscyamine is a tropane alkaloid and the levo-isomer of atropine. It is commonly extracted from plants in the Solanaceae or nightshade family. Research into the action of hyoscyamine in published literature dates back to 1826. Hyoscyami...
Etuvetidigene Autotemcel
go.drugbank.com/drugs/DB17593ApprovedInvestigationalEtuvetidigene autotemcel is an autologous gene therapy which includes hematopoietic stem cells (HSCs) that have been genetically modified ex vivo. First approved by the FDA on December 9, 2025, etuvetidigene autotemcel is used to treat W...
Rocatinlimab
go.drugbank.com/drugs/DB18809InvestigationalDespite its promising results, the long-term safety of rocatinlimab requires further investigation, as serious adverse events and injection reactions such as fever and chills have been reported.
Apadenoson
go.drugbank.com/drugs/DB05009InvestigationalApadenoson is a selective A2a adenosine receptor agonist designed for use as a pharmacologic stress agent in cardiac perfusion imaging studies.
Tetrahydrocannabivarin
go.drugbank.com/drugs/DB11755InvestigationalFurther evidence has also shown that THCV acts as an agonist of GPR55 and l-α-lysophosphatidylinositol (LPI) [A32974]. … Δ9-THC is currently available in several synthetic forms, including [Dronabinol], while purified or isolated THCV is not approved for any medical uses and is not available as any marketed products.
Tepoxalin
go.drugbank.com/drugs/DB11466ExperimentalVet approvedIt is primarily used to reduce inflammation and relief of pain caused by musculoskeletal disorders such as hip dysplasia and arthritis.
Methylmethionine chloride
go.drugbank.com/drugs/DB13250ExperimentalIn Japan, it is used as an over the counter product for gastrointestinal health support. It is also called "Vitamin U", but it is not a true vitamin.