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Evofosfamide
go.drugbank.com/drugs/DB06091InvestigationalTH-302 is a nitroimidazole-linked prodrug of a brominated derivative of an isophosphoramide mustard previously used in cancer drugs such as ifosfamide, cyclophosphamide, and glufosfamide. … TH-302 has been shown, in preclinical studies, to be both efficacious and well tolerated.
Synonyms: (1-methyl-2-nitro-1H-imidazol-5-YL)methyl N,N'-bis(2-bromoethyl)diamidophosphate, (1-methyl-2-nitro-1H-imidazole-5-yl)methyl N,N'-bis(2-bromoethyl) diamidophosphateILY101
go.drugbank.com/drugs/DB05059InvestigationalILY101 is designed to allow for lower daily doses and improved patient acceptance and tolerability in comparison to other products in this class of drugs. … ILY101 is being developed for the treatment of hyperphosphatemia in CKD patients on dialysis and works by reducing the systemic absorption of dietary phosphate.
Nefiracetam
go.drugbank.com/drugs/DB13082InvestigationalNefiracetam has been used in trials studying the treatment of Alzheimer's Disease.
Categories: Compounds used in a research, industrial, or household settingTGAAC09
go.drugbank.com/drugs/DB06363InvestigationaltgAAC09 is an investigational vaccine that utilizes an AAV vector to deliver genes that encode HIV proteins. … It was under investigation in clinical trials NCT00482027 and NCT00888446 for the treatment of HIV Infection.
Chlorotoxin I-131
go.drugbank.com/drugs/DB05462InvestigationalChlorotoxin I-131 is investigated in clinical trials for treating brain cancer. … The selective effects of Chlorotoxin I-131 are regulated by its action on MMP2 receptors.
Levoglucose
go.drugbank.com/drugs/DB12970InvestigationalLevoglucose has been used in trials studying the diagnostic of Bowel Cleansing Prior to Colonoscopy.
Categories: Compounds used in a research, industrial, or household settingPefloxacin
go.drugbank.com/drugs/DB00487ApprovedA synthetic broad-spectrum fluoroquinolone antibacterial agent active against most gram-negative and gram-positive bacteria.
Ocrylate
go.drugbank.com/drugs/DB15086ExperimentalOcrylate is under investigation in clinical trial NCT01918059 (Cosmetic Outcome Study of Lid Laceration Repair With Suture Versus Tissue Adhesive).
Categories: Compounds used in a research, industrial, or household settingOxytetracycline
go.drugbank.com/drugs/DB00595ApprovedInvestigationalVet approvedA tetracycline analog isolated from the actinomycete streptomyces rimosus and used in a wide variety of clinical conditions.
Oxtriphylline
go.drugbank.com/drugs/DB01303ApprovedIn the US, oxtriphylline is no longer available. … Once in the body, theophylline is released and acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator.