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Chlortetracycline
go.drugbank.com/drugs/DB09093ApprovedVet approvedWithdrawnIt was discovered in 1945 by the scientist, Benjamin Minge Duggar, working at Lederle Laboratories under the supervision of Yellapragada Subbarow. … He discovered that this antibiotic was the product of an actinomycete strain he cultured and obtained from a soil sample from a field in Missouri.
3,3'-diindolylmethane
go.drugbank.com/drugs/DB11875InvestigationalDiindolylmethane has been used in trials studying the prevention and treatment of SLE, Prostate Cancer, Cervical Dysplasia, Stage I Prostate Cancer, and Stage II Prostate Cancer, among others.
Categories: Compounds used in a research, industrial, or household settingATN-161
go.drugbank.com/drugs/DB05491InvestigationalIt inhibits the migration and adhesion of particular integrins on activated endothelial cells that play a critical role in tumor angiogenesis. … Since the expression of alpha(5)beta(1) integrin by cancer cells and the role of this molecule in tumor angiogenesis is similar across a range of different cancers, the therapeutic benefit of ATN-161 is
Podofilox
go.drugbank.com/drugs/DB01179ApprovedA lignan found in podophyllin resin from the roots of podophyllum plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. … It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives
Desonide
go.drugbank.com/drugs/DB01260ApprovedInvestigationalA nonfluorinated corticosteroid anti-inflammatory agent used topically for dermatoses.
Mixtures: APOLAR N, DESOLEX-NCategories: Corticosteroids, Moderately Potent (Group II)Dapsone
go.drugbank.com/drugs/DB00250ApprovedInvestigationalIt is also used with pyrimethamine in the treatment of malaria. (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8) … Its mechanism of action is probably similar to that of the sulfonamides which involves inhibition of folic acid synthesis in susceptible organisms.
Propyl Gallate
go.drugbank.com/drugs/DB12450InvestigationalPropyl Gallate is under investigation in clinical trial NCT01450098 (A Study of LY2484595 in Healthy Subjects).
Categories: Compounds used in a research, industrial, or household settingGuar gum
go.drugbank.com/drugs/DB13446InvestigationalCategories: Drugs Used in Diabetes, Compounds used in a research, industrial, or household settingPropidium
go.drugbank.com/drugs/DB02166ExperimentalQuaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes … with cholinesterase which it inhibits.
Categories: Compounds used in a research, industrial, or household settingDesloratadine
go.drugbank.com/drugs/DB00967ApprovedInvestigationalIt is the active descarboethoxy metabolite of loratidine (a second generation histamine). … Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral H1-antagonist action.