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Displaying results 3651 - 3660 of 10000 in total
  1. Drug

    Sucralose

    go.drugbank.com/drugs/DB15049
    Investigational

    Sucralose is an artificial sweetener used as a sugar substitute.

    Categories: Compounds used in a research, industrial, or household setting
  2. Drug

    Pramiracetam

    go.drugbank.com/drugs/DB13247
    Approved

    Pramiracetam has been studied for the use in Alzheimer's disease and as an adjunct treatment to restore cognitive functioning post-electroconvulsive therapy in severe depression [L5470]. … It was also previously approved in the United States with orphan drug designation [L1469].

  3. Drug

    Squalene

    go.drugbank.com/drugs/DB11460
    ApprovedInvestigationalVet approvedWithdrawn

    It is a natural 30-carbon isoprenoid compound and intermediate metabolite in the synthesis of cholesterol. It is not susceptible to lipid peroxidation and provides skin protection. … It is ubiquitously distributed in human tissues where it is transported in serum generally in association with very low density lipoproteins. Squalene is investigated as an adjunctive cancer therapy.

    Synonyms: (E,E,E,E)-Squalene, (all-E)-2,6,10,15,19,23-hexamethyl-2,6,10,14,18,22-tetracosahexaene
  4. Drug

    Temefos

    go.drugbank.com/drugs/DB12231
    Investigational

    Diphos has been used in trials studying the treatment of Plasmodium Falciparum Malaria.

    Categories: Compounds used in a research, industrial, or household setting
  5. Drug

    Chromanol

    go.drugbank.com/drugs/DB13111
    Investigational

    Chromanol has been used in trials studying the treatment of Prostate Cancer.

    Categories: Compounds used in a research, industrial, or household setting
  6. Drug

    Palonosetron

    go.drugbank.com/drugs/DB00377
    ApprovedInvestigational

    It is the most effective of the 5-HT3 antagonists in controlling delayed CINV nausea and vomiting that appear more than 24 hours after the first dose of a course of chemotherapy and is the only drug of … Palonosetron (INN, trade name Aloxi) is an antagonist of 5-HT3 receptors that is indicated for the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).

  7. Drug

    NOV-002

    go.drugbank.com/drugs/DB05393
    Investigational

    NOV-002, the lead compound acts as a chemoprotectant and an immunomodulator, in combination with chemotherapy. … NOV-002 is approved and marketed in the Russian Fereration by Pharma BAM under the trade name Glutoxim.

  8. Drug

    Valbenazine

    go.drugbank.com/drugs/DB11915
    ApprovedInvestigational

    [A261165] However, challenges in using [tetrabenazine] as a treatment of tardive dyskinesia included frequent dosing and safety and tolerability concerns. … The reduction in chorea severity was observed as early as 2 weeks after starting treatment with an initial dose of 40 mg.[L47910]

  9. Drug

    Beclamide

    go.drugbank.com/drugs/DB09011
    Experimental

    Beclamide (N-benzyl-B-chloropropionamide) is a no longer used drug that possesses anticonvulsant and sedative activity. … It was studied in the 1950s for generalised tonic-clonic seizures but was not effective for absence seizures.

  10. Drug

    Oleoyl-estrone

    go.drugbank.com/drugs/DB04870
    Investigational

    Oleoyl-estrone (OE) is a fatty acid ester of estrone. This hormone occurs naturally and is found circulating in various animal species and humans. … It has been shown in animal studies to promote the loss of body fat while maintaining body protein storage, maintaining nitrogen balance.