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Afamelanotide
go.drugbank.com/drugs/DB04931Approved[L9092] Despite its relatively recent approval, afamelanotide has been available for use as an orphan drug in both the US and EU since 2008.[L9122,L9125] … [L9086] It differs structurally from its endogenous counterpart by only two amino acids - these structural differences improve biological efficacy by imparting a greater affinity for its target and a longer
Categories: Compounds used in a research, industrial, or household settingAmilomotide
go.drugbank.com/drugs/DB05150InvestigationalCAD106 is an immunotherapeutic product in development for the treatment of Alzheimer's disease.
Naxitamab
go.drugbank.com/drugs/DB15965ApprovedInvestigationalNaxitamab (humanized 3F8, hu3F8) is an IgG1 monoclonal antibody directed against the oncofetal differentiation antigen GD2 disialoganglioside. … [L24454,A224604] Normally expressed during fetal development and in mature neurons, pain fibers, and skin cells, GD2 constitutes a highly efficient target in the treatment of neuroblastoma - it is widely
Bemiparin
go.drugbank.com/drugs/DB09258ApprovedInvestigationalWithdrawnLike semuloparin, bemiparin is classified as an ultra-LMH because of its low mean molecular mass of 3600 daltons, which is a unique property of this class [A7866]. … Bemiparin is an antithrombotic and belongs to the group of drugs known as the low molecular weight heparins (LMWH).
Amitraz
go.drugbank.com/drugs/DB11373ExperimentalVet approvedAmitraz presents insect repellent effects and hence, it can be used as an insecticide and pesticide. … Amitraz is a non-systemic acaricide and insecticide. It was generated in 1969 by the Boots Co. in England.
Categories: Compounds used in a research, industrial, or household settingMM-093
go.drugbank.com/drugs/DB05512InvestigationalMM-093 is a recombinant version of human alpha-fetoprotein (hAFP), an immunomodulatory serum protein normally produced at very high levels by the fetus and present in low levels in the blood of adults … Research on AFP suggests that it may play a role in modulating the immune system of the mother in order to protect the developing fetus during pregnancy.
OM85
go.drugbank.com/drugs/DB16533InvestigationalOM-85, a bacterial extract, is an immunomodulator of interferon-β production and inflammasome activity.
NC-6300
go.drugbank.com/drugs/DB17341ExperimentalNC-6300, also known as K-912, is a novel [epirubicin] drug-conjugated polymeric micelle.
P-BCMA-101
go.drugbank.com/drugs/DB17371InvestigationalP-BCMA-101 is an autologous CAR-T therapy developed using Poseida’s piggyBac platform technology.
Synonyms: Autologous T-cells transfected with PiggyBac transposon plasmid vector expressing B-cell maturation antigen (CAR-T cells)