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Aleglitazar
go.drugbank.com/drugs/DB08915InvestigationalIt is being investigated for use in patients with type II diabetes to reduce their risks of cardiovascular mortality and morbidity. … Aleglitazar is an agonist at the peroxisome proliferator-activated receptor (PPAR) for both the PPARα and PPARγ receptor subtypes.
Cloprednol
go.drugbank.com/drugs/DB13843InvestigationalCloprednol is a synthetic glucocorticoid that has been investigated for use in the treatment of asthma. [A31775,A31776]
Categories: Corticosteroids for Systemic Use, Corticosteroids for Systemic Use, PlainICA-105665
go.drugbank.com/drugs/DB06089InvestigationalICA-105665 is a novel small molecule compound for the treatment of epilepsy.
Aceclofenac
go.drugbank.com/drugs/DB06736ApprovedIt is reported to have a higher anti-inflammatory action or at least comparable effects than conventional NSAIDs in double-blind studies [A19667, A19668, A19670].
Categories: Topical Products for Joint and Muscular Pain, Antiinflammatory Preparations, Non-Steroids for Topical UsePlumbagin
go.drugbank.com/drugs/DB17048InvestigationalPlumbagin is a compound investigated for its anticancer activity. It has been found that it inactivates the Akt/NF-kB, MMP-9 and VEGF pathways.[A253102]
Categories: Hormonal Contraceptives for Systemic Use, Compounds used in a research, industrial, or household settingSolabegron
go.drugbank.com/drugs/DB06190InvestigationalSolabegron (GW-427,353) is a selective β3 adrenoceptor agonist being developed for the treatment of overactive bladder and irritable bowel syndrome.
Categories: Drugs for Urinary Frequency and IncontinenceGadoversetamide
go.drugbank.com/drugs/DB00538ApprovedGadoversetamide, marketed under the trade name OptiMARK, is a gadolinium compound used as a contrast agent in magnetic resonance imaging (MRI), particularly imaging of the brain, spine and liver.
Categories: Compounds used in a research, industrial, or household settingEtesevimab
go.drugbank.com/drugs/DB15897Investigational[L40174] The EUA currently allows bamlanivimab and etesevimab for post-exposure prophylaxis of COVID-19 in adults and children.[L40179] … [L16651,L16661] Under the EUA granted in February 2021, etesevimab is used in combination with [bamlanivimab] to treat mild to moderate COVID-19 in adults and pediatric patients who are at high risk for
Categories: Experimental Unapproved Treatments for COVID-19Omidenepag isopropyl
go.drugbank.com/drugs/DB15071Approved[A253253] In 2018, omidenepag isopropyl was approved in Japan for the treatment of glaucoma and ocular hypertension.[A253268] In September 2022, the FDA approved the use of omidenepag isopropyl. … [A253263,A253268] Prostanoid FP receptor agonists (FP agonists), such as [latanoprost], are part of the first-line therapy for ocular hypertension and primary open-angle glaucoma; however, not all patients
Sofpironium
go.drugbank.com/drugs/DB19325Approved[L51108,L51109] Sofpironium bromide (Sofdra) was approved by the FDA in June 2024 for the topical treatment of primary axillary hyperhidrosis. … [A264153] Sofpironium is rapidly converted to a less active metabolite, BBI-4010, after exerting its activity, thereby limiting the incidence and/or severity of systemic anticholinergic effects.