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Pol polyprotein
go.drugbank.com/bio_entities/BE0001400TargetFIVDuring replicative cycle of retroviruses, the reverse-transcribed viral DNA is integrated into the host chromosome by the viral integrase enzyme. RNase H activity is associated with the reverse transcriptase.
Polypeptides: Pol polyproteinIrbesartan
go.drugbank.com/drugs/DB01029ApprovedInvestigational[L7456,L7459] It can also be used as part of a combination product with [hydrochlorothiazide] for patients not well controlled or not expected to be well controlled on monotherapy. … Irbesartan is an angiotensin receptor blocker (ARB) indicated to treat hypertension or diabetic nephropathy.
Mixtures: Pro-irbesartan-hctz, Pro-irbesartan-hctzCategories: Antihypertensive Agents Indicated for HypertensionParoxetine
go.drugbank.com/drugs/DB00715ApprovedInvestigationalParoxetine is a selective serotonin reuptake inhibitor (SSRI) drug commonly known as Paxil. … Paroxetine is well tolerated in most patients with a similar adverse effect profile to other members of its drug class.
Categories: Antidepressive Agents Indicated for DepressionProducts: Pro-paroxetine, PAROXETIN 1A PHARMA 10MGNimesulide
go.drugbank.com/drugs/DB04743ApprovedWithdrawnNimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties.
Categories: Topical Products for Joint and Muscular Pain, Antiinflammatory Preparations, Non-Steroids for Topical UseProducts: KITEDO-LI, MESULID SUSPENSION AL 1 %Cardiolipin Biosynthesis (Barth Syndrome)
smpdb.ca/view/SMP0074684DiseaseA mutated tafazzin gene disrupts this post-synthetic remodeling and causes Barth syndrome (BTHS), an X-linked human disease (PMID: 16973164).
Citalopram
go.drugbank.com/drugs/DB00215ApprovedInvestigational[A261316,A14720] Specifically, it has a very minimal effect on dopamine and norepinephrine transportation and virtually no affinity for muscarinic, histaminergic, or GABAergic receptors. … It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs.
Categories: Monoamine Oxidase A Substrates, Antidepressive Agents Indicated for DepressionProducts: Pro-citalopram, CITALOPRAM 1A PHARMA 10MGAtomoxetine
go.drugbank.com/drugs/DB00289ApprovedInvestigational[A178090] Atomoxetine has been shown to specifically increase NA and DA within the prefrontal cortex, but not in the nucleus accumbens (NA) or striatum. … Many contain a blackbox warning stating that CNS stimulants, including methylphenidate-containing products and amphetamines, have a high potential for abuse and dependence.
Categories: Psychostimulants, Agents Used for ADHD and NootropicsProducts: Pro-atomoxetine, ATOMOXE 1A PHARMA 10MGMometasone furoate
go.drugbank.com/drugs/DB14512ApprovedInvestigationalVet approvedMometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its different indications[FDA Label][F4292,F4295]. … Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions[FDA Label][F4292,F4295].
Mixtures: M-FURO FA %0.1 + %2 KREM, 30 GCategories: Corticosteroids for inhalation use, Drugs for Obstructive Airway DiseasesApixaban
go.drugbank.com/drugs/DB06605ApprovedInvestigationalApixaban is an oral, direct, and highly selective factor Xa (FXa) inhibitor of both free and bound FXa, as well as prothrombinase, independent of antithrombin III for the prevention and treatment of thromboembolic
Categories: Factor Xa Inhibitors, Direct factor Xa inhibitorsProducts: Pro-apixaban, Apixaban 1A Pharma 5 mg – Filmtabletten