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Tolterodine
go.drugbank.com/drugs/DB01036ApprovedInvestigationalTolterodine is an antimuscarinic drug that is used to treat urinary incontinence. Tolterodine acts on M2 and M3 subtypes of muscarinic receptors.
Products: TOLTERODIN 1A PHA4MG HA RE, Detrol LAGentamicin
go.drugbank.com/drugs/DB00798ApprovedInvestigationalVet approvedGentamicin is a bactericidal aminoglycoside that was discovered and isolated from _Micromonospora purpurea_ in 1963. … [A234359,A234364] Although gentamicin is well-established and may be used in a variety of clinical applications, it is also associated with severe adverse effects including nephrotoxicity and ototoxicity
Mixtures: Amolg A, SAEROGENTA-A CREAMCategories: OCT2 Substrates with a Narrow Therapeutic Index, Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexPancrelipase
go.drugbank.com/drugs/DB00085ApprovedInvestigational[L2509] The pancrelipase mixture was developed by Ortho-McNeil-Janssen Pharmaceuticals, Inc and FDA approved on April 12, 2010. … Pancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and proteases. These enzymes are extracted from porcine pancreatic glands.
Products: CREON® CAPSULAS DE LIBERACION RETARADADA 10.000, PANZYTRAT OK MA RE MICROTAVincristine
go.drugbank.com/drugs/DB00541ApprovedInvestigationalVincristine is an antitumor vinca alkaloid isolated from Vinca Rosea. It is marketed under several brand names, many of which have different formulations such as Marqibo (liposomal injection) and Vincasar. Vincristine is indicated for th...
Categories: BSEP/ABCB11 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: SULFATO DE VINCRISTINA 1 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE.Leucovorin
go.drugbank.com/drugs/DB00650ApprovedInvestigationalLeucovorin, also known as folinic acid or citrovorum factor, is a reduced form of folic acid that serves as a vital coenzyme in nucleic acid synthesis. … [L56091, L56092] Historically developed in 1945, leucovorin has long been a staple on the World Health Organization’s List of Essential Medicines.
Mixtures: BumP DHA, BumP DHACategories: Compounds used in a research, industrial, or household settingMeropenem
go.drugbank.com/drugs/DB00760ApprovedInvestigationalMeropenem is a broad-spectrum carbapenem antibiotic. It is active against Gram-positive and Gram-negative bacteria. … In August 2017, a combination antibacterial therapy under the market name vabomere was approved for treatment of adult patients with complicated urinary tract infections (cUTI).
Products: Meropenem Dr. F. Eberth 2 g Pulver zur Herstellung einer Injektions-/Infusionslösung, Meropenem Dr. F. Eberth 1 g Pulver zur Herstellung einer Injektionslösung oder InfusionslösungPemetrexed
go.drugbank.com/drugs/DB00642ApprovedInvestigationalPemetrexed was first approved by the FDA in February 4, 2004.[A253907] … Pemetrexed is a chemotherapy drug that is manufactured and marketed by Eli Lilly and Company under the brand name Alimta.
Categories: OAT3/SLC22A8 Substrates with a Narrow Therapeutic Index, Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexProducts: PEMETREXED DR. REDDY'S, PEMETREXED 500 MG POLVO LIOFILIZADO PARA SOLUCIÓN DE INFUSIÓN.Risperidone
go.drugbank.com/drugs/DB00734ApprovedInvestigational[L12885] Risperidone binds with a very high affinity to 5-HT2A receptors, approximately 10-20 fold greater than the drug's binding affinity to D2 receptors, and carries lesser activity at several off-targets … Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and mental health conditions including schizophrenia and bipolar disorder.
Categories: Dopamine D2 Receptor AntagonistsProducts: RISPERIDONE DI RENZO, RISPERIDONE DR. REDDY'SFamotidine
go.drugbank.com/drugs/DB00927ApprovedInvestigationalFamotidine is a competitive histamine-2 (H<sub>2</sub>) receptor antagonist that works to inhibit gastric acid secretion. … disease, famotidine was about 20 to 50 times more potent at inhibiting gastric acid secretion than [cimetidine] and eight times more potent than [ranitidine] on a weight basis.
Mixtures: DG Health Dual Action Complete, DG Health acid reducer completeProducts: Dg Health Acid Reducer, Dg Health Heartburn PreventionAmbrisentan
go.drugbank.com/drugs/DB06403ApprovedInvestigationalIt is approved in Europe, Canada and the United States for use as a single agent to improve exercise ability and delay clinical worsening. … Ambrisentan is an orally active selective type A endothelin receptor antagonist indicated for the treatment of pulmonary arterial hypertension.
Products: AMBRISENTAN DR. REDDY?S, AMBRISEN 1A PHARMA 5MG