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Donepezil
go.drugbank.com/drugs/DB00843ApprovedInvestigationalDonepezil was first approved by the FDA in 1996, and its extended-release form was approved in combination with [Memantine] in 2014 to manage moderate and severe forms of Alzheimer's dementia. … In 2016, the global burden of dementia was estimated to be 43.8 million, demonstrating a significant increase from a global prevalence of 20.2 million in 1990.
Products: DONEPEZIL EG, TABLET 10MGIsotretinoin
go.drugbank.com/drugs/DB00982ApprovedInvestigational[L6574] Isotretinoin is associated with major risks in pregnancy and is therefore only available under the iPLEDGE program in the United States. … [L6579] The first isotretinoin-containing product was FDA approved on 7 May 1982.[L6574]
Categories: Retinoids for Topical Use in AcneProducts: ISOTRETINOINA EG, ISODERM 10MGCholine
go.drugbank.com/drugs/DB00122ApprovedInvestigationalNutraceuticalIt is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism. … A basic constituent of lecithin that is found in many plants and animal organs.
Mixtures: Super Stress Mega B Plus 1000mg Vit C Tab, Doctor's Choice Brand for MenSynonyms: N,N,N-trimethylethanol-ammonium, N-trimethylethanolamineLabetalol
go.drugbank.com/drugs/DB00598ApprovedInvestigational[L7730] Labetalol is formulated as an injection or tablets to treat hypertension.[L7727,L7730] Labetalol was granted FDA approval on 1 August 1984.[L7724]
Products: Trandate Tab 100mg, Trandate Tablets 100mgFulvestrant
go.drugbank.com/drugs/DB00947ApprovedInvestigationalIt is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and by degrading the estrogen receptor. … Fulvestrant is a drug treatment of hormone receptor (HR)-positive metastatic breast cancer in post-menopausal women with disease progression following anti-estrogen therapy.
Products: FULVESTRANT 250 MG/5ML SOLUCION INYECTABLE EN JERIGA PRECARGADA, FULTRANT ® 250MG/ 5ML SOLUCIÓN PARA INYECCIÓN EN JERINGA PRELLENADASodium citrate
go.drugbank.com/drugs/DB09154ApprovedInvestigationalIt is white, crystalline powder or white, granular crystals, slightly deliquescent in moist air, freely soluble in water, practically insoluble in alcohol. Like citric acid, it has a sour taste. … It works by neutralizing excess acid in the blood and urine. It has been indicated for the treatment of metabolic acidosis.
Mixtures: Enl, N-ORS Oral Rehydration Salts (Orange Flavour)Categories: Compounds used in a research, industrial, or household settingPalbociclib
go.drugbank.com/drugs/DB09073ApprovedInvestigationalPalbociclib is a piperazine pyridopyrimidine[A176792] that acts in the cell cycle machinery. … [L5867] It was originally FDA approved on March 2015 for the treatment of HR-positive, HER2-negative advanced or metastatic breast cancer and its indications were updated in April 2019 to include male
Products: Ibrance Capsules 100mg, IBRANCE CAPSULE 100mgSiltuximab
go.drugbank.com/drugs/DB09036ApprovedInvestigationalSiltuximab is a chimeric (human-mouse) monoclonal immunoglobulin G1-kappa antibody produced in a Chinese hamster ovary (CHO) cell line by recombinant DNA technology.
Products: Sylvant 100mg Powder for Concentrate for Solution for Infusion, SYLVANT POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 100MG/VIALMetoclopramide
go.drugbank.com/drugs/DB01233ApprovedInvestigationalIt is available in the oral tablet form or in solution, and can also be administered through the intravenous route.[T683] Metoclopramide was initially approved by the FDA in 1980.[A184922] … Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system.
Synonyms: 2-methoxy-4-amino-5-chloro-N,N-(dimethylaminoethyl)benzamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-o-anisamideProducts: METOPRAX 10 MG/2 ML IM/IV ENJ. COZ. ICEREN AMPUL, 5 ADET, Reglan Tab 10mgDiamorphine
go.drugbank.com/drugs/DB01452ApprovedIllicit(Merck Index, 11th ed) Internationally, diamorphine is controlled under Schedules I and IV of the Single Convention on Narcotic Drugs. … It is a controlled substance (opium derivative) listed in the U.S. Code of Federal Regulations, Title 21 Parts 329.1, 1308.11 (1987). Sale is forbidden in the United States by Federal statute.
Categories: Drugs Used in Opioid Dependence, Drugs Used in Addictive DisordersProducts: Diamorphine Hydrochloride Inj 100mg/ml BP