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Displaying results 3691 - 3700 of 10000 in total
  1. Target

    5'-AMP-activated protein kinase

    go.drugbank.com/bio_entities/BE0004907
    TargetTransporterHumans

    Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism (PubMed:17307971, PubMed:17712357, PubMed:24563466, PubMed:31492851, PubMed:37821951...

    Polypeptides: 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit beta-2
  2. Target

    Keratin, type II cytoskeletal 5

    go.drugbank.com/bio_entities/BE0009087
    TargetHumans

    Structural component of intermediate filaments in basal keratinocytes of stratified epithelia. Forms heteropolymers with type I partners including KRT14 and KRT15, contributing to the formation of the keratin intermediate filament networ...

    Polypeptides: Keratin, type II cytoskeletal 5Synonyms: CK-5, Keratin-5
  3. Target

    Protein arginine N-methyltransferase 5

    go.drugbank.com/bio_entities/BE0011121
    TargetHumans

    Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA (PubMed:10531356, PubMed:11152681, PubMed:11747828, P...

    Polypeptides: Protein arginine N-methyltransferase 5
  4. Target

    Inositol polyphosphate 5-phosphatase OCRL

    go.drugbank.com/bio_entities/BE0013933
    EnzymeHumans

    Also, is able to hydrolyze the 5-phosphate of inositol 1,4,5-trisphosphate and of inositol 1,3,4,5-tetrakisphosphate (PubMed:15474001, PubMed:40969890, PubMed:7761412). … Catalyzes the hydrolysis of the 5-position phosphate of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and phosphatidylinositol-3,4,5-bisphosphate (PtdIns(3,4,5)P3), with the greatest catalytic

    Polypeptides: Inositol polyphosphate 5-phosphatase OCRLSynonyms: Inositol polyphosphate 5-phosphatase OCRL-1, Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase
  5. Target

    Splicing factor 3B subunit 5

    go.drugbank.com/bio_entities/BE0018936
    TargetHumans

    Component of the 17S U2 SnRNP complex of the spliceosome, a large ribonucleoprotein complex that removes introns from transcribed pre-mRNAs (PubMed:12234937, PubMed:27720643, PubMed:28781166, PubMed:32494006, PubMed:34822310). The 17S U2...

    Polypeptides: Splicing factor 3B subunit 5
  6. Drug

    Lutetium Lu 177 dotatate

    go.drugbank.com/drugs/DB13985
    ApprovedInvestigational

    In terms of biodistribution, Lutetium Lu 177 dotatate demonstrated a lower whole-body retention, indicating potentially lower risk for bone marrow toxicity [A31696]. … A 177Lu-labeled somatostatin analog peptide, Lutetium Lu 177 dotatate belongs to an emerging form of treatments called Peptide Receptor Radionuclide Therapy (PRRT), which involves targeting tumours with

    Categories: Compounds used in a research, industrial, or household settingSynonyms: Lutetium Lu 177 DOTA(0)-Tyr(3)-Octreotate, 177-Lu DOTA-0-Tyr3-Octreotate
  7. Drug

    Dobesilic acid

    go.drugbank.com/drugs/DB13529
    Investigational

    Products: X-VEN 500 MG KAPSÜL,30 ADET, X-VEN 500 MG KAPSÜL,60 ADET
  8. Drug

    Antithrombin III human

    go.drugbank.com/drugs/DB11598
    ApprovedInvestigational

    A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.

    Synonyms: Heparin cofactor BProducts: Antithrombin III "Takeda" 50 I.E./ml Pulver und Lösungsmittel zur Herstellung einer Injektionslösung, ANBİNEX 500 IU/10 ML IV İNFÜZYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON VE ÇÖZÜCÜSÜ
  9. Drug

    Manganese cation

    go.drugbank.com/drugs/DB06757
    ApprovedInvestigationalNutraceutical

    Manganese is a transition metal that was first described in the 19th and 20th centuries. … [A263687, A263662] In humans, manganese regulates several physiological processes by acting as a cofactor for proteins [A263657, A263662, A263667] making it an essential metal for normal development and

    Mixtures: Calcium With Mg Zn Mn Cu CR Si and Vit. C & D, TRACUTIL® 10 ML AMPOLLASSynonyms: MANGANESE(2+), MANGANESE ION(2+)
  10. Drug

    Levosulpiride

    go.drugbank.com/drugs/DB16021
    Investigational

    Mixtures: LEPRIT® ENZIMATICOGRAGEAS, LEPRIT® ENZIMATICOGRAGEASSynonyms: S-(-)-Sulpiride