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Pegsunercept
go.drugbank.com/drugs/DB06611InvestigationalPegsunercept is used for treating rheumatoid arthritis. Phase II clinical trials were completed in January 2010.
Categories: Compounds used in a research, industrial, or household settingDifamilast
go.drugbank.com/drugs/DB14987ApprovedInvestigationalThe drug is indicated for the topical treatment of mild to moderate atopic dermatitis in adults and pediatric patients 2 years of age and older [L55042]. It is approved in Japan and the United States. … [A275420] Difamilast is a selective PDE4 inhibitor and the inhibition of phosphodiesterase-4 (PDE4) reduces proinflammatory mediators and cytokines in atopic dermatitis.
Synonyms: 地法米司特Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InducersIofetamine I-123
go.drugbank.com/drugs/DB09480ApprovedSynonyms: Iofetamine I 123, Iofetamine I-123Salts: Iofetamine hydrochloride I-123Toluene
go.drugbank.com/drugs/DB11558InvestigationalVet approvedToluene is a colorless, liquid that is immiscible in water. It is a mono-substituted benzene derivative used in veterinary medicine as a treatment for various parasites in dogs and cats.
Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 SubstratesFerric ammonium citrate
go.drugbank.com/drugs/DB09501ApprovedWithdrawnMixtures: Iron, Vit & Min SuppProducts: KİNAMALT SİROP, 250 G, FOLITON 250 MG/5 ML ŞURUP, 120 MLSonlicromanol
go.drugbank.com/drugs/DB16333InvestigationalSonlicromanol is under investigation in clinical trial NCT04165239 (The KHENERGYZE Study).
Synonyms: (S)-6-Hydroxy-2,5,7,8-Tetramethyl-N-((R)-Piperidin-3-Yl)Chroman-2-CarboxamideCategories: Compounds used in a research, industrial, or household setting, Vitamin E, analogs & derivativesManganese citrate
go.drugbank.com/drugs/DB14495ApprovedMixtures: Collag-EN, Tricare Prenatal 2-part Daily Prenatal Vitamin SystemLevomethadone
go.drugbank.com/drugs/DB13515InvestigationalSynonyms: l-methadoneCategories: Drugs Used in Opioid Dependence, Drugs Used in Addictive DisordersRabeprazole
go.drugbank.com/drugs/DB01129ApprovedInvestigationalRabeprazole is an antiulcer drug in the class of proton pump inhibitors. It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form. … Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal and stimulated gastric acid secretion.
Categories: Cytochrome P-450 Substrates, 2-PyridinylmethylsulfinylbenzimidazolesProducts: RABEPRAZOLO EG, Rabeprazole ECLefamulin
go.drugbank.com/drugs/DB12825Approved[A183206] Lefamulin is available in intravenous and oral preparations and was granted FDA approval in August 2019. … A pleuromotilin is a more recently developed type of antibiotic that is derived from the fungus, Pleurotus mutilus.
Categories: P-glycoprotein substrates, Cytochrome P-450 Substrates