This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Ferric ammonium citrate
- DrugBank Accession Number
- DB09501
- Background
Not Available
- Type
- Small Molecule
- Groups
- Approved, Experimental
- Structure
Structure for Ferric ammonium citrate (DB09501)
- Weight
- Average: 264.997
Monoisotopic: 264.986842 - Chemical Formula
- C6H11FeNO7
- Synonyms
- Ferric ammonium citrate
- Ferric ammonium citrate, green
- External IDs
- E 381
- E-381
- INS NO.381
- INS-381
Pharmacology
- Indication
Not Available
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Avoid life-threatening adverse drug eventsImprove clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events & improve clinical decision support.- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareAlendronic acid Ferric ammonium citrate can cause a decrease in the absorption of Alendronic acid resulting in a reduced serum concentration and potentially a decrease in efficacy. Almasilate Almasilate can cause a decrease in the absorption of Ferric ammonium citrate resulting in a reduced serum concentration and potentially a decrease in efficacy. Aluminium phosphate Aluminium phosphate can cause a decrease in the absorption of Ferric ammonium citrate resulting in a reduced serum concentration and potentially a decrease in efficacy. Aluminum hydroxide Aluminum hydroxide can cause a decrease in the absorption of Ferric ammonium citrate resulting in a reduced serum concentration and potentially a decrease in efficacy. Asenapine Asenapine can cause a decrease in the absorption of Ferric ammonium citrate resulting in a reduced serum concentration and potentially a decrease in efficacy. Calcium carbonate Calcium carbonate can cause a decrease in the absorption of Ferric ammonium citrate resulting in a reduced serum concentration and potentially a decrease in efficacy. Calcium Phosphate Ferric ammonium citrate can cause a decrease in the absorption of Calcium Phosphate resulting in a reduced serum concentration and potentially a decrease in efficacy. Calcium phosphate dihydrate Ferric ammonium citrate can cause a decrease in the absorption of Calcium phosphate dihydrate resulting in a reduced serum concentration and potentially a decrease in efficacy. Carbidopa Ferric ammonium citrate can cause a decrease in the absorption of Carbidopa resulting in a reduced serum concentration and potentially a decrease in efficacy. Cefdinir Ferric ammonium citrate can cause a decrease in the absorption of Cefdinir resulting in a reduced serum concentration and potentially a decrease in efficacy. 
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- No interactions found.
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Deriton Ferric ammonium citrate (50 mg / 15 mL) + Choline bitartrate (50 mg / 15 mL) + Cyanocobalamin (14 mcg / 15 mL) + Dexpanthenol (5 mg / 15 mL) + Ergocalciferol (400 unit / 15 mL) + Inositol (50 mg / 15 mL) + Nicotinamide (45 mg / 15 mL) + Pyridoxine hydrochloride (2.5 mg / 15 mL) + Racemethionine (50 mg / 15 mL) + Riboflavin (5 mg / 15 mL) + Thiamine mononitrate (4.5 mg / 15 mL) + Vitamin A palmitate (5000 unit / 15 mL) Liquid Oral Nutrimetics International (Canada) Inc. 1985-12-31 1996-09-09 Canada 
Geritol Liquid Ferric ammonium citrate (1 mg / mL) + Dexpanthenol (.34 mg / mL) + Nicotinamide (1 mg / mL) + Pyridoxine hydrochloride (.07 mg / mL) + Riboflavin (.17 mg / mL) + Thiamine hydrochloride (.1 mg / mL) Liquid Oral Glaxosmithkline Inc 1992-12-31 2002-07-31 Canada Heparos Ampoules Buvables Ferric ammonium citrate (4.2 mg / 10 mL) + Cyanocobalamin (50 mcg / 10 mL) Liquid Oral Desbergers LtÉe, Division Of Technilab Inc. 1987-12-31 1999-09-17 Canada Iron, Vit & Min Supp Ferric ammonium citrate (30 mg / tab) + Choline bitartrate (82 mg / tab) + Copper gluconate (1 mg / tab) + Cyanocobalamin (14 mcg / tab) + D-alpha-Tocopherol acetate (10 unit / tab) + Folic acid (.1 mg / tab) + Niacin (2.5 mg / tab) + Nicotinamide (7.5 mg / tab) + Pantothenic acid (5 mg / tab) + Pyridoxine (1.5 mg / tab) + Riboflavin (1.2 mg / tab) + Thiamine (1 mg / tab) Tablet Oral Avacare, Division Of Jeunique International Inc. 1985-12-31 1996-09-09 Canada Maltlevol 12 Liq Ferric ammonium citrate (2.4 mg / mL) + Cyanocobalamin (.311 mcg / mL) + Nicotinamide (.667 mg / mL) + Pyridoxine (.067 mg / mL) + Riboflavin (.067 mg / mL) + Thiamine (.1 mg / mL) + Vitamin A (133 unit / mL) + Vitamin D (8.9 unit / mL) + Vitamin E (.56 unit / mL) Liquid Oral Carter Horner Corp. 1978-12-31 2002-02-07 Canada Maltlevol Liq Ferric ammonium citrate (2.4 mg / mL) + Nicotinamide (.22 mg / mL) + Pyridoxine (.033 mg / mL) + Riboflavin (.044 mg / mL) + Thiamine (.044 mg / mL) + Vitamin A (111 unit / mL) + Vitamin D (8.9 unit / mL) + Vitamin E (.56 unit / mL) Liquid Oral Carter Horner Corp. 1980-12-31 2005-03-21 Canada Nrg Plus Liq Ferric ammonium citrate (15 mg / 15 mL) + Biotin (100 mcg / 15 mL) + Cholecalciferol (400 unit / 15 mL) + Choline bitartrate (50 mg / 15 mL) + Cyanocobalamin (14 mcg / 15 mL) + Dexpanthenol (15 mg / 15 mL) + Flavin mononucleotide (7.5 mg / 15 mL) + Inositol (50 mg / 15 mL) + Nicotinamide (45 mg / 15 mL) + Potassium Iodide (.1 mg / 15 mL) + Potassium citrate (200 mg / 15 mL) + Pyridoxine hydrochloride (3 mg / 15 mL) + Thiamine mononitrate (4.5 mg / 15 mL) + Vitamin A palmitate (5000 unit / 15 mL) Liquid Oral Jeunique International Inc. 1998-02-17 2006-07-20 Canada
Categories
- ATC Codes
- V08CA07 — Ferric ammonium citrate
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- UVP74NG1C5
- CAS number
- 1185-57-5
- InChI Key
- FRHBOQMZUOWXQL-UHFFFAOYSA-N
- InChI
- InChI=1S/C6H8O7.Fe.H3N/c7-3(8)1-6(13,5(11)12)2-4(9)10;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;1H3/q;+3;
- IUPAC Name
- iron(3+) 2-hydroxypropane-1,2,3-tricarboxylic acid amine
- SMILES
- N.[Fe+3].OC(=O)CC(O)(CC(O)=O)C(O)=O
References
- General References
- Not Available
- External Links
- ChemSpider
- 2006378
- 24897
- Wikipedia
- Ammonium_ferric_citrate
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Granule, effervescent Syrup Oral Tablet Oral Liquid Oral - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 106.0 mg/mL ALOGPS logP -1.3 ALOGPS logP -1.3 ChemAxon logS -0.26 ALOGPS pKa (Strongest Acidic) 3.05 ChemAxon pKa (Strongest Basic) -4.2 ChemAxon Physiological Charge -3 ChemAxon Hydrogen Acceptor Count 7 ChemAxon Hydrogen Donor Count 4 ChemAxon Polar Surface Area 132.13 Å2 ChemAxon Rotatable Bond Count 5 ChemAxon Refractivity 35.62 m3·mol-1 ChemAxon Polarizability 15.51 Å3 ChemAxon Number of Rings 0 ChemAxon Bioavailability 1 ChemAxon Rule of Five Yes ChemAxon Ghose Filter No ChemAxon Veber's Rule No ChemAxon MDDR-like Rule No ChemAxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
Drug created at November 30, 2015 19:10 / Updated at May 21, 2021 10:21