Ferric ammonium citrate

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Ferric ammonium citrate
DrugBank Accession Number
DB09501
Background

Not Available

Type
Small Molecule
Groups
Approved, Experimental
Structure
Thumb
Weight
Average: 264.997
Monoisotopic: 264.986842
Chemical Formula
C6H11FeNO7
Synonyms
  • Ferric ammonium citrate
  • Ferric ammonium citrate, green
External IDs
  • E 381
  • E-381
  • INS NO.381
  • INS-381

Pharmacology

Indication

Not Available

Pharmacology
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Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Adverseeffects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
Alendronic acidFerric ammonium citrate can cause a decrease in the absorption of Alendronic acid resulting in a reduced serum concentration and potentially a decrease in efficacy.
AlmasilateAlmasilate can cause a decrease in the absorption of Ferric ammonium citrate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Aluminium phosphateAluminium phosphate can cause a decrease in the absorption of Ferric ammonium citrate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Aluminum hydroxideAluminum hydroxide can cause a decrease in the absorption of Ferric ammonium citrate resulting in a reduced serum concentration and potentially a decrease in efficacy.
AsenapineAsenapine can cause a decrease in the absorption of Ferric ammonium citrate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium carbonateCalcium carbonate can cause a decrease in the absorption of Ferric ammonium citrate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium PhosphateFerric ammonium citrate can cause a decrease in the absorption of Calcium Phosphate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium phosphate dihydrateFerric ammonium citrate can cause a decrease in the absorption of Calcium phosphate dihydrate resulting in a reduced serum concentration and potentially a decrease in efficacy.
CarbidopaFerric ammonium citrate can cause a decrease in the absorption of Carbidopa resulting in a reduced serum concentration and potentially a decrease in efficacy.
CefdinirFerric ammonium citrate can cause a decrease in the absorption of Cefdinir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Interactions
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Food Interactions
No interactions found.

Products

Products2
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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
DeritonFerric ammonium citrate (50 mg / 15 mL) + Choline bitartrate (50 mg / 15 mL) + Cyanocobalamin (14 mcg / 15 mL) + Dexpanthenol (5 mg / 15 mL) + Ergocalciferol (400 unit / 15 mL) + Inositol (50 mg / 15 mL) + Nicotinamide (45 mg / 15 mL) + Pyridoxine hydrochloride (2.5 mg / 15 mL) + Racemethionine (50 mg / 15 mL) + Riboflavin (5 mg / 15 mL) + Thiamine mononitrate (4.5 mg / 15 mL) + Vitamin A palmitate (5000 unit / 15 mL)LiquidOralNutrimetics International (Canada) Inc.1985-12-311996-09-09Canada flag
Geritol LiquidFerric ammonium citrate (1 mg / mL) + Dexpanthenol (.34 mg / mL) + Nicotinamide (1 mg / mL) + Pyridoxine hydrochloride (.07 mg / mL) + Riboflavin (.17 mg / mL) + Thiamine hydrochloride (.1 mg / mL)LiquidOralGlaxosmithkline Inc1992-12-312002-07-31Canada flag
Heparos Ampoules BuvablesFerric ammonium citrate (4.2 mg / 10 mL) + Cyanocobalamin (50 mcg / 10 mL)LiquidOralDesbergers LtÉe, Division Of Technilab Inc.1987-12-311999-09-17Canada flag
Iron, Vit & Min SuppFerric ammonium citrate (30 mg / tab) + Choline bitartrate (82 mg / tab) + Copper gluconate (1 mg / tab) + Cyanocobalamin (14 mcg / tab) + D-alpha-Tocopherol acetate (10 unit / tab) + Folic acid (.1 mg / tab) + Niacin (2.5 mg / tab) + Nicotinamide (7.5 mg / tab) + Pantothenic acid (5 mg / tab) + Pyridoxine (1.5 mg / tab) + Riboflavin (1.2 mg / tab) + Thiamine (1 mg / tab)TabletOralAvacare, Division Of Jeunique International Inc.1985-12-311996-09-09Canada flag
Maltlevol 12 LiqFerric ammonium citrate (2.4 mg / mL) + Cyanocobalamin (.311 mcg / mL) + Nicotinamide (.667 mg / mL) + Pyridoxine (.067 mg / mL) + Riboflavin (.067 mg / mL) + Thiamine (.1 mg / mL) + Vitamin A (133 unit / mL) + Vitamin D (8.9 unit / mL) + Vitamin E (.56 unit / mL)LiquidOralCarter Horner Corp.1978-12-312002-02-07Canada flag
Maltlevol LiqFerric ammonium citrate (2.4 mg / mL) + Nicotinamide (.22 mg / mL) + Pyridoxine (.033 mg / mL) + Riboflavin (.044 mg / mL) + Thiamine (.044 mg / mL) + Vitamin A (111 unit / mL) + Vitamin D (8.9 unit / mL) + Vitamin E (.56 unit / mL)LiquidOralCarter Horner Corp.1980-12-312005-03-21Canada flag
Nrg Plus LiqFerric ammonium citrate (15 mg / 15 mL) + Biotin (100 mcg / 15 mL) + Cholecalciferol (400 unit / 15 mL) + Choline (50 mg / 15 mL) + Cyanocobalamin (14 mcg / 15 mL) + Dexpanthenol (15 mg / 15 mL) + Flavin mononucleotide (7.5 mg / 15 mL) + Inositol (50 mg / 15 mL) + Nicotinamide (45 mg / 15 mL) + Potassium (200 mg / 15 mL) + Potassium Iodide (.1 mg / 15 mL) + Pyridoxine hydrochloride (3 mg / 15 mL) + Thiamine mononitrate (4.5 mg / 15 mL) + Vitamin A palmitate (5000 unit / 15 mL)LiquidOralJeunique International Inc.1998-02-172006-07-20Canada flag

Categories

ATC Codes
V08CA07 — Ferric ammonium citrate
Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
UVP74NG1C5
CAS number
1185-57-5
InChI Key
FRHBOQMZUOWXQL-UHFFFAOYSA-N
InChI
InChI=1S/C6H8O7.Fe.H3N/c7-3(8)1-6(13,5(11)12)2-4(9)10;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;1H3/q;+3;
IUPAC Name
iron(3+) 2-hydroxypropane-1,2,3-tricarboxylic acid amine
SMILES
N.[Fe+3].OC(=O)CC(O)(CC(O)=O)C(O)=O

References

General References
Not Available
ChemSpider
2006378
RxNav
24897
Wikipedia
Ammonium_ferric_citrate

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Granule, effervescent
SyrupOral
TabletOral
LiquidOral
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility106.0 mg/mLALOGPS
logP-1.3ALOGPS
logP-1.3ChemAxon
logS-0.26ALOGPS
pKa (Strongest Acidic)3.05ChemAxon
pKa (Strongest Basic)-4.2ChemAxon
Physiological Charge-3ChemAxon
Hydrogen Acceptor Count7ChemAxon
Hydrogen Donor Count4ChemAxon
Polar Surface Area132.13 Å2ChemAxon
Rotatable Bond Count5ChemAxon
Refractivity35.62 m3·mol-1ChemAxon
Polarizability15.51 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created on November 30, 2015 19:10 / Updated on May 21, 2021 10:21