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Methyprylon
go.drugbank.com/drugs/DB01107ApprovedIllicitWithdrawnMethyprylon is a sedative of the piperidinedione derivative family that was previously used for the treatment of insomnia.
Daclizumab
go.drugbank.com/drugs/DB00111ApprovedInvestigationalWithdrawnHumanized IgG1 Mab that binds to the human interleukin-2 receptor (anti-Tac or anti-CD25). Daclizumab is a composite of human (90%) and murine (10%) antibody sequences. … in de novo allogeneic renal transplantation and used concomitantly with an immunosuppressive regimen like cyclosporine and corticosteroids in patients who are not hight immunized, for commercial reasons
Categories: Interleukin-2 Receptor Antagonist, Interleukin-2 Receptor Blocking AntibodyIsoconazole
go.drugbank.com/drugs/DB08943ApprovedIsoconazole is an azole antifungal drug that has similar effectiveness to clotrimazole in the treatment of foot and vaginal infections.
Categories: Antifungals for Topical Use, Antifungals for Dermatological UseAprepitant
go.drugbank.com/drugs/DB00673ApprovedInvestigationalAprepitant, an antiemetic, is a substance P/neurokinin 1 (NK1) receptor antagonist which, in combination with other antiemetic agents, is indicated for the prevention of acute and delayed nausea and vomiting … Aprepitant is a selective high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors.
Categories: Substance P/Neurokinin-1 Receptor Antagonist, Neurokinin-1 Receptor AntagonistsBucetin
go.drugbank.com/drugs/DB13278ApprovedWithdrawnBucetin is an analgesic and antipyretic medication which was approved for use in Germany but was withdrawn from the market in 1986 due to renal toxicity caused by the medication.[A175636]
Dicyclomine
go.drugbank.com/drugs/DB00804ApprovedInvestigational[L7982] Dicyclomine was granted FDA approval on 11 May 1950.[L7967] … [A6556,A182555,A234659,L7967] Though it is commonly prescribed, its recommendation may have been based on a small amount of evidence and so its prescription is becoming less favourable.
Categories: Drugs for Functional Gastrointestinal DisordersFentonium
go.drugbank.com/drugs/DB08978ApprovedWithdrawnFentonium is an atropine derivative.
Categories: Drugs for Functional Gastrointestinal DisordersPefloxacin
go.drugbank.com/drugs/DB00487ApprovedA synthetic broad-spectrum fluoroquinolone antibacterial agent active against most gram-negative and gram-positive bacteria.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseTacrine
go.drugbank.com/drugs/DB00382ApprovedWithdrawnTacrine has been discontinued for the United States market.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesRibostamycin
go.drugbank.com/drugs/DB03615ApprovedWithdrawnRibostamycin is an aminoglycoside antibiotic[A187166] isolated from _Streptomyces ribosidificus_[A187178] listed as one of the World Health Organization's critically important antimicrobials.[L9071]
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use