Ribostamycin is a broad spectrum aminoglycoside antibiotic on the list of WHO critical antimicrobials for human medicine. Ribostamycin is an aminoglycoside antibiotic isolated from Streptomyces ribosidificus listed as one of the World Health Organization's critically important antimicrobials.
- Mechanism
- Curator reviewed
Aminoglycosides work by binding to the bacterial 30S ribosomal subunit (some work by binding to the 50S subunit), inhibiting the translocation of the peptidyl-tRNA from the A-site to the P-site and also causing misreading of mRNA, leaving the bacterium unable to synthesize proteins vital to its growth. However, their exact mechanism of action is not fully known.
- Formula / weight
- C17H34N4O10 · 454.4727 g/mol (avg)
- Also known as
- Ribostamycin A · Vistamycin
- Code names
- Antibiotic SF 733 · Bu 1709 · SF-733
Resolves to
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Which drugs share a target with Ribostamycin, and which of those have an active Phase 3 trial?
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