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Displaying results 3711 - 3720 of 7603 in total
  1. Drug

    αAβ–Gas6

    go.drugbank.com/drugs/DB17069
    Experimental

    αAβ–Gas6 is a chimeric fusion protein being investigated in preclinical studies as an immunotherapeutic agent for Alzheimer's disease (AD). … made of a single chain variable fragment (scFv) of an Amyloid β (Aβ)-targeting monoclonal antibody fused with a truncated receptor binding domain of growth arrest-specific 6 (Gas6), which is a ligand for

  2. Drug

    Triazavirin

    go.drugbank.com/drugs/DB15622
    Investigational

    [L12087] Given the similarities between SARS-CoV-2 and H5N1, health officials are investigating Triazavirin as an option to combat SARS-CoV-2, the coronavirus responsible for COVID-19.[A191625]

    Categories: Antivirals for Systemic Use, Antiinfectives for Systemic Use
  3. Drug

    GC-376 free acid

    go.drugbank.com/drugs/DB15796
    Experimental

    These results suggest that GC-376, and its metabolites may have therapeutic potential for Covid-19. … GC-376 is a 3C-like protease (3CL<sup>pro</sup> or M<sup>pro</sup>) inhibitor that stops the cleavage and activation of functional viral proteins required for replication and transcription in host cells

    Categories: Experimental Unapproved Treatments for COVID-19
  4. Drug

    GT 389-255

    go.drugbank.com/drugs/DB05894
    Experimental

    Peptimmune’s lead product GT 389-255, is a novel lipase inhibitor and fat binding hydrogel polymer conjugate for the treatment of obesity which has completed single and multiple ascending dose (SAD and

  5. Drug

    Odanacatib

    go.drugbank.com/drugs/DB06670
    Investigational

    Odanacatib is an inhibiter of cathepsin K which was originally developed be Merck & Co as a new treatment for osteoporosis [A19388].

  6. Drug

    Tricaine

    go.drugbank.com/drugs/DB11552
    ExperimentalVet approved

    It is also the only anesthetic licensed in the United States for use in fin fish that are intended for human consumption. … Tricaine (as tricaine methanesulfonate) is white powder used for anesthesia, sedation, or euthanasia of fish.

  7. Drug

    V590

    go.drugbank.com/drugs/DB16437
    Experimental

    Merck is currently underway to begin Phase I trials for the vaccine through intramuscular administration (NCT04569786). … By teaming up with IAVI, Merk developed a vaccine that does not require freezing, and only requires one dose[L30583].

  8. Drug

    Nabiximols

    go.drugbank.com/drugs/DB14011
    Investigational

    While cannabis in its natural plant form is currently used "off-label" for the management of many medical conditions, THC is currently commercially available in synthetic form as [DB00486], as purified … Sativex® is available in a 1:1 formulation of THC:CBD as an oro-mucosal pump spray used for treatment of neuropathic pain from Multiple Sclerosis (MS) and for intractable cancer pain.

  9. Drug

    Encenicline

    go.drugbank.com/drugs/DB11726
    Investigational

    Encenicline has been investigated for the treatment of Cognition, Schizophrenia, Alzheimer's Disease, Cardiac Repolarization, and Central Nervous System Diseases.

  10. Drug

    Stavudine

    go.drugbank.com/drugs/DB00649
    ApprovedInvestigational

    A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.

    Categories: Antivirals for Systemic Use, Antiinfectives for Systemic Use