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Displaying results 3711 - 3720 of 4860 in total
  1. Drug

    Ifenprodil

    go.drugbank.com/drugs/DB08954
    ApprovedInvestigationalWithdrawn

    [A220133] Further studies elucidated that ifenprodil binds strongly at the inter-subunit interface of adjacent GluN1 and GluN2B NTDs, where it acts as a non-competitive antagonist. … A220118, A220128] Although ifenprodil has received considerable interest in its potential neuromodulatory activities in psychiatric conditions, including dependency[A220138] and depression,[A220143] it

  2. Drug

    Reglitazar

    go.drugbank.com/drugs/DB04971
    Experimental

    It is the first non-thiazolidenedione to enter clinical trials.

  3. Drug

    Amonafide

    go.drugbank.com/drugs/DB05022
    Investigational

    It belongs to the families of drugs called topoisomerase inhibitors and intercalating agents.

  4. Drug

    Sulforaphane

    go.drugbank.com/drugs/DB12422
    Investigational

    It is a naturally occurring isothiocyanate found in high concentration in a variety of broccoli.

  5. Drug

    Atigotatug

    go.drugbank.com/drugs/DB14831
    Investigational

    It is under investigation in clinical trial NCT02815592 (Trial of BMS-986012 in Combination With Platinum and Etoposide).

  6. Drug

    Apazunersen

    go.drugbank.com/drugs/DB16981
    Investigational

    It is being investigated for the treatment of Angelman Syndrome.[L46772]

  7. Drug

    Antimony potassium tartrate

    go.drugbank.com/drugs/DB15587
    Experimental

    It has irritant emetic properties and may cause lethal cardiac toxicity among other adverse effects.

  8. Drug

    Porphobilinogen

    go.drugbank.com/drugs/DB02272
    Experimental

    It is generated by the enzyme ALA dehydratase, and converted into hydroxymethyl bilane by the enzyme porphobilinogen deaminase.

  9. Drug

    Pumactant

    go.drugbank.com/drugs/DB04955
    Experimental

    It is a unique formulation of the naturally occurring phospholipids Dipalmitoylphosphatidycholine (DPPC) and Phosphatidyl Glycerol (PG).

  10. Drug

    AT9283

    go.drugbank.com/drugs/DB05169
    Investigational

    It was discovered and developed internally using Astex’s fragment-based drug discovery platform, Pyramid.