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Bioallethrin
go.drugbank.com/drugs/DB13746ApprovedWithdrawnBioallethrin is a synthetic pyrethroid used as a pesticide against household pest insects such as mosquitoes, houseflies and cockroaches. It is claimed to have low mammalian toxicity. … A mixture containing only S-forms of allethrin is referred to as esbioallethrin or S-bioallethrin.
Categories: Compounds used in a research, industrial, or household settingRevumenib
go.drugbank.com/drugs/DB18515ApprovedInvestigationalMenin is a scaffold protein that interacts with both the wild-type and rearranged KMT2A, which is crucial for KMT2A activity and the maintenance of _HOXA_ expression and leukemogenesis.
Xenon Xe-129
go.drugbank.com/drugs/DB17386ApprovedInvestigationalLung MRIs are challenging due to the low proton density of this tissue, as well as the presence of artifacts due to respiration and cardiovascular pulsation movement and air–tissue interfaces. … They undergo a process that increases nuclear polarization up to five orders of magnitude, leading to a higher MRI signal.
Synonyms: Xenon, isotope of mass 129m(8.88 d)Mifamurtide
go.drugbank.com/drugs/DB13615ApprovedInvestigationalAlso called L-MTP-PE, mifamurtide may be a liposomal form of of the active ingredient MTP-PE, which is a synthetic, less pyrogenic, and longer-acting derivative of muramyl dipeptide (MDP). … As a liposomal formulation, mifamurtide demonstrates an enhanced tumoricidal effect and improved safety profile [A31745]. Mifamurtide is marketed in Europe as Mepact for intravenous infusion.
Pemivibart
go.drugbank.com/drugs/DB18720Investigational[L51733] Due to the amino acid substitutions in the Fc region (M435L/N441A), pemivibart has an extended serum half-life.[L51728] … Pemivibart (Pemgarda) is a human IgG1 monoclonal antibody targeting the SARS-CoV-2 spike protein receptor binding domain.
Vosoritide
go.drugbank.com/drugs/DB11928ApprovedInvestigational[A242273] While the remarkably short half-life of endogenous CNP - 2 to 3 minutes due to its rapid degradation by endopeptidases - makes it ineffective as a therapeutic intervention,[A242273] the development … of a peptidase-resistant formulation has allowed for its use as a viable treatment option in achondroplasia.
Ginger
go.drugbank.com/drugs/DB10344ApprovedInvestigationalGinger allergenic extract is used in allergenic testing.
Mixtures: C Ottways Lax TabAlogliptin
go.drugbank.com/drugs/DB06203ApprovedInvestigationalAlogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase-4 (DPP-4). … Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (>99%). It undergoes little or no chiral conversion in vivo to the (S)-enantiomer.
Mixtures: INCRESINA DUOPovidone
go.drugbank.com/drugs/DB11061ApprovedInvestigationalWithdrawnPovidone, also known as polyvinylpyrrolidone (PVP) or polyvidone, is a synthetic water-soluble polymer made from the monomer N-vinylpyrrolidone used as a binder in many pharmaceutical tablets and lubricant … When in complex with iodine, [DB06812] displays antiseptic properties where the iodine, a bactericidal component, mainly contributes to this effect, and povidone acts as a carrier [A32988].
Mixtures: DG Health Sterile Advanced Relief Eye, DG Health Advanced Relief Eye DropsCategories: Compounds used in a research, industrial, or household settingOmbitasvir
go.drugbank.com/drugs/DB09296ApprovedInvestigationalIn a joint recommendation published in 2016, the American Association for the Study of Liver Diseases (AASLD) and the Infectious Diseases Society of America (IDSA) recommend Ombitasvir as a first line … therapy option when used in combination with other antivirals for genotypes 1a, 1b, and 4 [L852].