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Resiquimod
go.drugbank.com/drugs/DB06530InvestigationalIt is also being studied to find out if adding it to a tumor vaccine improves the antitumor immune response. It is a type of imidazoquinoline and a type of immunomodulator. … A substance being studied in the treatment of some types of skin cancer. When put on the skin, resiquimod causes some immune cells to make certain chemicals that may help them kill tumor cells.
Categories: Heterocyclic Compounds, 1-RingIsatoribine
go.drugbank.com/drugs/DB04860ExperimentalIsatoribine is a selective agonist of TLR7.
Categories: Heterocyclic Compounds, 2-RingSynonyms: 7-Deaza-7-thia-8-oxoguanosine, 7-Thia-8-oxoguanosineNBI-6024
go.drugbank.com/drugs/DB05819InvestigationalNBI-6024 is an altered peptide ligand that is designed to cause an immune response which result in preservation of beta-cell function and endogenous insulin production.
Aldoxorubicin
go.drugbank.com/drugs/DB06013InvestigationalAldoxorubicin, an antineoplastic agents, is an albumin-binding prodrug of doxorubicin.
Seproxetine
go.drugbank.com/drugs/DB06731ExperimentalSeproxetine is also known as (S)-norfluoxetine. It is a selective serotonin reuptake inhibitor (SSRI). It is an active metabolite of fluoxetine.
Categories: Cytochrome P-450 CYP2C19 Inhibitors, Cytochrome P-450 CYP2C9 InhibitorsSynonyms: (S)-norfluoxetineApolizumab
go.drugbank.com/drugs/DB06467InvestigationalApolizumab is a humanized monoclonal antibody that is being studied as a treatment for hematologic cancers.
Synonyms: (SUB 1)-CHAIN), DISULPHIDE WITH HUMAN-MOUSE MONOCLONAL HU1D10 LIGHT CHAIN, DIMERZYC300
go.drugbank.com/drugs/DB04986InvestigationalZYC300 is a plasmid DNA of CYP1B1 encapsulated in biodegradable poly-DL-lactide-coglycolide microparticles. … It is designed as a vaccine, intended to increase immune system sensitivity to CYP1B1, an enzyme highly prevalent in tumor cells.
TBC-3711
go.drugbank.com/drugs/DB05407InvestigationalTBC3711 is a next-generation endothelin antagonist that is being studied through oral and intravenous formulations by Encysive Pharmaceuticals.
Categories: Endothelin A Receptor Antagonists, Heterocyclic Compounds, 1-Ring3,4-Methylenedioxy-N-isopropylamphetamine
go.drugbank.com/drugs/DB06112ExperimentalMDI-P is also a potential therapeutic agent for the treatment of the symptoms of cystic fibrosis ("CF"). … MDI-P has demonstrated potent anti-HIV activity. MDI-P has been shown to be effective in killing HIV in cell culture. HIV is the virus that causes acquired immune deficiency syndrome (AIDS).
Synonyms: MDI-P, 3,4-Methylenedioxy-N-isopropylamphetamineCefodizime
go.drugbank.com/drugs/DB13470InvestigationalCefodizime is a third generation cephalosporin with a broad spectrum of antibacterial activity.[A275053, A275058]
Categories: Heterocyclic Compounds, 2-Ring