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Displaying results 3751 - 3760 of 10000 in total
  1. Drug

    Metformin

    go.drugbank.com/drugs/DB00331
    ApprovedInvestigational

    It is commonly described as an "insulin sensitizer", leading to a decrease in insulin resistance and a clinically significant reduction of plasma fasting insulin levels. … Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes.

    Mixtures: JARDIANCE DUO® 5 MG/1000 MG, JARDIANCE DUO® 5 MG / 850 MGCategories: MATE 1 Substrates, MATE 2 Substrates
  2. Drug

    Abiprubart

    go.drugbank.com/drugs/DB19333
    Investigational

    Abiprubart is being evaluated for its efficacy and safety in participants with Sjögren's Disease in clinical trial NCT06531395

    Synonyms: (115-212), hinge 1-12 S10>P (222) (213-224), CH2 L, Gamma4 heavy chain humanized (1-441) [VH (Homo sapiens IGHV1-3*01 (83.7%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.7] (26-33.51-58.97-103)) (1-114)-Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10 (CH1
  3. Drug

    Ilacirnon

    go.drugbank.com/drugs/DB16066
    Investigational

    Ilacirnon (CCX-140) is under investigation in clinical trial NCT01440257 (A Study to Evaluate the Effect of CCX140-B on Urinary Albumin Excretion in Subjects With Type 2 Diabetes and Albuminuria).

    Synonyms: 4-Chloro-N-[5-methyl-2-(7H-pyrrolo[2,3-d]pyrimidin-4-ylcarbonyl)-3-pyridinyl]-3-(trifluoromethyl)benzenesulfonamide
  4. Drug

    (1S,2R,5S)-5-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-2-(2,4,5-TRIFLUOROPHENYL)CYCLOHEXANAMINE

    go.drugbank.com/drugs/DB07072
    Experimental

    Synonyms: (1S,2R,5S)-5-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-2-(2,4,5-TRIFLUOROPHENYL)CYCLOHEXANAMINE
  5. Drug

    Combretastatin A4

    go.drugbank.com/drugs/DB14680
    Experimental

    Synonyms: Combretastatin A-4, PHENOL, 2-METHOXY-5-(2-(3,4,5-TRIMETHOXYPHENYL)ETHENYL)-, (Z)-
  6. Drug

    Coptisine

    go.drugbank.com/drugs/DB19308
    Experimental

    Synonyms: 6,7-dihydrobis(1,3)benzodioxolo(5,6-a:4',5'-g)quinolizinium, Bis(1,3)benzodioxolo(5,6-a:4',5'-g)quinolizinium, 6,7-dihydro-Categories: Heterocyclic Compounds with 4 or More Rings
  7. Drug

    2-(4-(2-((3-(5-(PYRIDIN-2-YLTHIO)THIAZOL-2-YL)UREIDO)METHYL)-1H-IMIDAZOL-4-YL)PHENOXY)ACETIC ACID

    go.drugbank.com/drugs/DB08657
    Experimental

    Synonyms: 2-(4-(2-((3-(5-(PYRIDIN-2-YLTHIO)THIAZOL-2-YL)UREIDO)METHYL)-1H-IMIDAZOL-4-YL)PHENOXY)ACETIC ACIDCategories: Heterocyclic Compounds, 1-Ring
  8. Drug

    ESK981

    go.drugbank.com/drugs/DB18155
    Investigational

    Synonyms: 4h-indazolo(5,4-a)pyrrolo(3,4-c)carbazol-4-one, 2,5,6,11,12,13-hexahydro-2-methyl-11-(2-methylpropyl)-8-(2-pyrimidinylamino)-, 4-methylbenzenesulfonate (1:1)Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  9. Drug

    Ketotifen

    go.drugbank.com/drugs/DB00920
    ApprovedInvestigational

    It has a similar structure to some other first-generation antihistamines such as [cyproheptadine] and [azatadine]. … [A231204] In the US, it is now used in an over-the-counter ophthalmic formulation for the treatment of itchy eyes associated with allergies,[L32278] and in Canada a prescription-only oral formulation is

    Categories: Heterocyclic Compounds, 1-Ring, Histamine H1 InhibitorsProducts: KETOTIFENE EG, KETEN SYRUP 1 mg/5 ml
  10. Drug

    Ezabenlimab

    go.drugbank.com/drugs/DB17483
    Investigational

    Synonyms: Anti-pd-1 monoclonal antibody bi 754091, Immunoglobulin g4 (228-proline), anti-(human programmed cell death protein 1) (human monoclonal bi754091 .gamma.4-chain), disulfide with human monoclonal bi754091 .kappa.-chain, dimer